Reliable serodiagnosis of imported cystic echinococcosis with a commercial indirect hemagglutination assay

H. Rogier van Doorn; Henk Hofwegen; Rob Koelewijn; Henk Gilis; Ellen Wentink-Bonnema; Elena Pinelli; Perry J. J. van Genderen; Hans G. Schipper; Tom van Gool

doi:https://doi.org/10.1016/j.diagmicrobio.2006.10.002

Reliable serodiagnosis of imported cystic echinococcosis with a commercial indirect hemagglutination assay

H. Rogier van Doorn, Henk Hofwegen, Rob Koelewijn, Henk Gilis, Ellen Wentink-Bonnema, Elena Pinelli, Perry J. J. van Genderen, Hans G. Schipper, Tom van Gool

Research output: Contribution to journal › Article › Academic › peer-review

14 Citations (Scopus)

Abstract

A commercially available indirect hemagglutination assay (IHA) (Echinococcosis Fumouze; Laboratoires Fumouze, Levallois-Perret, France) was evaluated using sera from 52 patients with proven cystic echinococcosis. The specificity was assessed using 247 sera from patients with various parasitic, bacterial, viral, and fungal infectious diseases; sera containing autoimmune antibodies; and sera from healthy blood donors. With a cutoff value for a positive result of 320 (as recommended by the manufacturer), the sensitivity and specificity were 88% and 98.4%; with a cutoff of 160, the sensitivity and specificity were 94% and 95.1%, respectively. The IHA is rapid, easy to perform, and is a very sensitive serodiagnostic test for cystic echinococcosis

Original language	English
Pages (from-to)	409-412
Journal	Diagnostic microbiology and infectious disease
Volume	57
Issue number	4
DOIs	https://doi.org/10.1016/j.diagmicrobio.2006.10.002
Publication status	Published - 2007

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https://doi.org/10.1016/j.diagmicrobio.2006.10.002

Cite this

van Doorn, H. R., Hofwegen, H., Koelewijn, R., Gilis, H., Wentink-Bonnema, E., Pinelli, E., van Genderen, P. J. J., Schipper, H. G., & van Gool, T. (2007). Reliable serodiagnosis of imported cystic echinococcosis with a commercial indirect hemagglutination assay. Diagnostic microbiology and infectious disease, 57(4), 409-412. https://doi.org/10.1016/j.diagmicrobio.2006.10.002

@article{5c83b506685c4a6087f747dff52d2636,

title = "Reliable serodiagnosis of imported cystic echinococcosis with a commercial indirect hemagglutination assay",

abstract = "A commercially available indirect hemagglutination assay (IHA) (Echinococcosis Fumouze; Laboratoires Fumouze, Levallois-Perret, France) was evaluated using sera from 52 patients with proven cystic echinococcosis. The specificity was assessed using 247 sera from patients with various parasitic, bacterial, viral, and fungal infectious diseases; sera containing autoimmune antibodies; and sera from healthy blood donors. With a cutoff value for a positive result of 320 (as recommended by the manufacturer), the sensitivity and specificity were 88% and 98.4%; with a cutoff of 160, the sensitivity and specificity were 94% and 95.1%, respectively. The IHA is rapid, easy to perform, and is a very sensitive serodiagnostic test for cystic echinococcosis",

author = "{van Doorn}, {H. Rogier} and Henk Hofwegen and Rob Koelewijn and Henk Gilis and Ellen Wentink-Bonnema and Elena Pinelli and {van Genderen}, {Perry J. J.} and Schipper, {Hans G.} and {van Gool}, Tom",

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van Doorn, HR, Hofwegen, H, Koelewijn, R, Gilis, H, Wentink-Bonnema, E, Pinelli, E, van Genderen, PJJ, Schipper, HG & van Gool, T 2007, 'Reliable serodiagnosis of imported cystic echinococcosis with a commercial indirect hemagglutination assay', Diagnostic microbiology and infectious disease, vol. 57, no. 4, pp. 409-412. https://doi.org/10.1016/j.diagmicrobio.2006.10.002

TY - JOUR

T1 - Reliable serodiagnosis of imported cystic echinococcosis with a commercial indirect hemagglutination assay

AU - van Doorn, H. Rogier

AU - Hofwegen, Henk

AU - Koelewijn, Rob

AU - Gilis, Henk

AU - Wentink-Bonnema, Ellen

AU - Pinelli, Elena

AU - van Genderen, Perry J. J.

AU - Schipper, Hans G.

AU - van Gool, Tom

PY - 2007

Y1 - 2007

N2 - A commercially available indirect hemagglutination assay (IHA) (Echinococcosis Fumouze; Laboratoires Fumouze, Levallois-Perret, France) was evaluated using sera from 52 patients with proven cystic echinococcosis. The specificity was assessed using 247 sera from patients with various parasitic, bacterial, viral, and fungal infectious diseases; sera containing autoimmune antibodies; and sera from healthy blood donors. With a cutoff value for a positive result of 320 (as recommended by the manufacturer), the sensitivity and specificity were 88% and 98.4%; with a cutoff of 160, the sensitivity and specificity were 94% and 95.1%, respectively. The IHA is rapid, easy to perform, and is a very sensitive serodiagnostic test for cystic echinococcosis

AB - A commercially available indirect hemagglutination assay (IHA) (Echinococcosis Fumouze; Laboratoires Fumouze, Levallois-Perret, France) was evaluated using sera from 52 patients with proven cystic echinococcosis. The specificity was assessed using 247 sera from patients with various parasitic, bacterial, viral, and fungal infectious diseases; sera containing autoimmune antibodies; and sera from healthy blood donors. With a cutoff value for a positive result of 320 (as recommended by the manufacturer), the sensitivity and specificity were 88% and 98.4%; with a cutoff of 160, the sensitivity and specificity were 94% and 95.1%, respectively. The IHA is rapid, easy to perform, and is a very sensitive serodiagnostic test for cystic echinococcosis

U2 - https://doi.org/10.1016/j.diagmicrobio.2006.10.002

DO - https://doi.org/10.1016/j.diagmicrobio.2006.10.002

M3 - Article

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SN - 0732-8893

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JO - Diagnostic microbiology and infectious disease

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