Abstract
Successful pathogens have evolved a variety of specific gene products that facilitate their survival and growth within the host, as well as mechanisms to regulate expression of these virulence-associated genes in response to their environment. In comparison with commensals, the pathogenic phenotype can thus be seen as a consequence of both differences in gene content and gene expression. Not surprisingly, identification of these differences is a frequent goal in modern biomedical research, and as a result, a variety of differential screening methods have been developed over the last few years (1,2)
Original language | English |
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Pages (from-to) | 231-255 |
Journal | Methods in molecular medicine |
Volume | 67 |
DOIs | |
Publication status | Published - 2001 |