TY - JOUR
T1 - Research Gaps in Diet and Nutrition in Inflammatory Bowel Disease. A Topical Review by D-ECCO Working Group [Dietitians of ECCO]
AU - Sigall-Boneh, Rotem
AU - Levine, Arie
AU - Lomer, Miranda
AU - Wierdsma, Nicolette
AU - Allan, Philip
AU - Fiorino, Gionata
AU - Gatti, Simona
AU - Jonkers, Daisy
AU - Kierkus, Jaroslaw
AU - Katsanos, Konstantinos H
AU - Melgar, Silvia
AU - Yuksel, Elif Saritas
AU - Whelan, Kevin
AU - Wine, Eytan
AU - Gerasimidis, Konstantinos
PY - 2017/12/4
Y1 - 2017/12/4
N2 - Although the current doctrine of IBD pathogenesis proposes an interaction between environmental factors and gut microbiota in genetically susceptible individuals, dietary exposures have attracted recent interest and are, at least in part, likely to explain the rapid rise in disease incidence and prevalence. The D-ECCO working group along with other ECCO experts with expertise in nutrition, microbiology, physiology, and medicine reviewed the evidence investigating the role of diet and nutritional therapy in the onset, perpetuation, and management of IBD. A narrative topical review is presented where evidence pertinent to the topic is summarised collectively under three main thematic domains: i] the role of diet as an environmental factor in IBD aetiology; ii] the role of diet as induction and maintenance therapy in IBD; and iii] assessment of nutritional status and supportive nutritional therapy in IBD. A summary of research gaps for each of these thematic domains is proposed, which is anticipated to be agenda-setting for future research in the area of diet and nutrition in IBD.
AB - Although the current doctrine of IBD pathogenesis proposes an interaction between environmental factors and gut microbiota in genetically susceptible individuals, dietary exposures have attracted recent interest and are, at least in part, likely to explain the rapid rise in disease incidence and prevalence. The D-ECCO working group along with other ECCO experts with expertise in nutrition, microbiology, physiology, and medicine reviewed the evidence investigating the role of diet and nutritional therapy in the onset, perpetuation, and management of IBD. A narrative topical review is presented where evidence pertinent to the topic is summarised collectively under three main thematic domains: i] the role of diet as an environmental factor in IBD aetiology; ii] the role of diet as induction and maintenance therapy in IBD; and iii] assessment of nutritional status and supportive nutritional therapy in IBD. A summary of research gaps for each of these thematic domains is proposed, which is anticipated to be agenda-setting for future research in the area of diet and nutrition in IBD.
KW - Journal Article
U2 - https://doi.org/10.1093/ecco-jcc/jjx109
DO - https://doi.org/10.1093/ecco-jcc/jjx109
M3 - Article
C2 - 28961811
SN - 1873-9946
VL - 11
SP - 1407
EP - 1419
JO - Journal of Crohn's & Colitis
JF - Journal of Crohn's & Colitis
IS - 12
ER -