TY - JOUR
T1 - Respiratory Pathogen Detection in Children: Saliva as a Diagnostic Specimen
AU - de Koff, Emma M.
AU - Euser, Sjoerd M.
AU - Badoux, Paul
AU - Sluiter-Post, Judith
AU - Eggink, Dirk
AU - Sanders, Elisabeth A. M.
AU - van Houten, Marlies A.
N1 - Publisher Copyright: © 2021 Lippincott Williams and Wilkins. All rights reserved.
PY - 2021
Y1 - 2021
N2 - We compared pathogen detection between saliva, nasopharyngeal and oropharyngeal swabs in children with respiratory symptoms. The sensitivity in nasopharyngeal swabs was 93% (95% confidence interval [CI]: 78%-98%), in oropharyngeal swabs 79% (95% CI: 60%-90%), in saliva overall 76% (95% CI: 58%-88%) and in 18 saliva samples collected with drooling or sponges, 94% (95% CI: 74%-99%). Saliva could be a relevant specimen alternative.
AB - We compared pathogen detection between saliva, nasopharyngeal and oropharyngeal swabs in children with respiratory symptoms. The sensitivity in nasopharyngeal swabs was 93% (95% confidence interval [CI]: 78%-98%), in oropharyngeal swabs 79% (95% CI: 60%-90%), in saliva overall 76% (95% CI: 58%-88%) and in 18 saliva samples collected with drooling or sponges, 94% (95% CI: 74%-99%). Saliva could be a relevant specimen alternative.
KW - diagnostics
KW - pediatrics
KW - respiratory pathogens
KW - saliva
UR - http://www.scopus.com/inward/record.url?scp=85112773443&partnerID=8YFLogxK
U2 - https://doi.org/10.1097/INF.0000000000003191
DO - https://doi.org/10.1097/INF.0000000000003191
M3 - Article
C2 - 34260500
SN - 0891-3668
SP - E351-E353
JO - Pediatric Infectious Disease Journal
JF - Pediatric Infectious Disease Journal
ER -