Revascularization strategies for patients with established chronic coronary syndrome

Casper F. Coerkamp, Marieke Hoogewerf, Bart P. van Putte, Yolande Appelman, Pieter A. Doevendans

Research output: Contribution to journalReview articleAcademicpeer-review


Coronary artery disease is the most common type of cardiovascular disease, leading to high mortality rates worldwide. Although the vast majority can be treated effectively and safely by medical therapy, revascularization strategies remain essential for numerous patients. Outcomes of both percutaneous coronary intervention and coronary artery bypass grafting improve in a rapid pace, resulting from technical innovation and ongoing research. Progress has been achieved by technical improvements in coronary stents, optimal coronary target and graft selection, and the availability of minimally invasive surgical strategies. Besides technical progress, evidence-based patient-tailored decision-making by the Heart Team is the basic precondition for optimal outcome. The combination of fast innovation and long-term clinical evaluations creates a dynamic field. Research outcomes should be carefully interpreted according to the techniques used and the trial's design. Therefore, more and more trial outcomes suggest that revascularization strategies should be tailored towards the specific patient. Although the European Society of Cardiology/European Association for Cardio-Thoracic Surgery guidelines on myocardial revascularization date from 2018 and a large variety of trial outcomes on revascularization strategies in chronic coronary syndrome have been published since, we aim to provide an updated overview within this review.
Original languageEnglish
Article numbere13787
JournalEuropean journal of clinical investigation
Issue number8
Early online date2022
Publication statusPublished - Aug 2022


  • chronic coronary syndrome
  • coronary revascularization
  • patient-tailored

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