TY - JOUR
T1 - Role of Polyethylene Glycol in the Treatment of Functional Constipation in Children
AU - Koppen, Ilan J. N.
AU - Broekaert, Ilse J.
AU - Wilschanski, Michael
AU - Papadopoulou, Alexandra
AU - Ribes-Koninckx, Carmen
AU - Thapar, Nikhil
AU - Gottrand, Frederic
AU - Orel, Rok
AU - Lionetti, Paolo
AU - Benninga, Marc A.
PY - 2017
Y1 - 2017
N2 - According to international guidelines, polyethylene glycol (PEG) is the laxative of first choice in the treatment of functional constipation in children, both for disimpaction and for maintenance treatment. PEG acts as an osmotic laxative and its efficacy is dose dependent. PEG is highly effective, has a good safety profile, and is well tolerated by children. Only minor adverse events have been reported. Overall the use of PEG in children has been reported to be safe, although in patients predisposed to water and electrolyte imbalances monitoring of serum electrolytes should be considered
AB - According to international guidelines, polyethylene glycol (PEG) is the laxative of first choice in the treatment of functional constipation in children, both for disimpaction and for maintenance treatment. PEG acts as an osmotic laxative and its efficacy is dose dependent. PEG is highly effective, has a good safety profile, and is well tolerated by children. Only minor adverse events have been reported. Overall the use of PEG in children has been reported to be safe, although in patients predisposed to water and electrolyte imbalances monitoring of serum electrolytes should be considered
U2 - https://doi.org/10.1097/MPG.0000000000001704
DO - https://doi.org/10.1097/MPG.0000000000001704
M3 - Article
C2 - 28777126
SN - 0277-2116
VL - 65
SP - 361
EP - 363
JO - Journal of pediatric gastroenterology and nutrition
JF - Journal of pediatric gastroenterology and nutrition
IS - 4
ER -