Routine Chest Computed Tomography for Staging of Pancreatic Head Carcinoma

Dianne Leeuw; Bobby K Pranger; Koert P de Jong; Jan Pieter Pennings; Vincent E de Meijer; Joris I Erdmann

doi:https://doi.org/10.1097/MPA.0000000000001494

Routine Chest Computed Tomography for Staging of Pancreatic Head Carcinoma

Dianne Leeuw, Bobby K Pranger, Koert P de Jong, Jan Pieter Pennings, Vincent E de Meijer, Joris I Erdmann

Surgery (AMC)

Research output: Contribution to journal › Article › Academic › peer-review

1 Citation (Scopus)

Abstract

OBJECTIVES: The diagnostic value of routine chest computed tomography (CT) in addition to abdominal CT in workup for pancreatic head carcinoma is unclear. The aim of this study was to determine if routine chest CT revealed significant lesions that altered the management of patients with suspected pancreatic head carcinoma.

METHODS: All Dutch pancreatic cancer centers were surveyed on the use of chest CT in preoperative staging. In addition, a single-center retrospective cohort study was performed including all patients referred with suspected pancreatic head malignancy without chest CT between 2005 and 2016. The primary end point was the proportion of patients in which chest CT revealed clinically significant lesions, leading to a change in management.

RESULTS: In 7 of 18 Dutch pancreatic cancer centers (39%), a preoperative chest CT is not routinely performed. In the study cohort, 170 of 848 patients (20%) were referred without chest CT and underwent one by local protocol. Chest CT revealed new suspicious lesions in 17 patients (10%), of whom 6 had metastatic disease (3.5%).

CONCLUSIONS: Routine use of chest CT in diagnostic workup for pancreatic head carcinoma reveals clinically significant lesions in 10% of patients, being metastases in up to 4%.

Original language	English
Pages (from-to)	387-392
Number of pages	6
Journal	Pancreas
Volume	49
Issue number	3
DOIs	https://doi.org/10.1097/MPA.0000000000001494
Publication status	Published - 1 Mar 2020

Keywords

multiple pulmonary nodules
pancreas
pancreatic neoplasms
solitary pulmonary nodule
x-ray computed tomography

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title = "Routine Chest Computed Tomography for Staging of Pancreatic Head Carcinoma",

abstract = "OBJECTIVES: The diagnostic value of routine chest computed tomography (CT) in addition to abdominal CT in workup for pancreatic head carcinoma is unclear. The aim of this study was to determine if routine chest CT revealed significant lesions that altered the management of patients with suspected pancreatic head carcinoma.METHODS: All Dutch pancreatic cancer centers were surveyed on the use of chest CT in preoperative staging. In addition, a single-center retrospective cohort study was performed including all patients referred with suspected pancreatic head malignancy without chest CT between 2005 and 2016. The primary end point was the proportion of patients in which chest CT revealed clinically significant lesions, leading to a change in management.RESULTS: In 7 of 18 Dutch pancreatic cancer centers (39%), a preoperative chest CT is not routinely performed. In the study cohort, 170 of 848 patients (20%) were referred without chest CT and underwent one by local protocol. Chest CT revealed new suspicious lesions in 17 patients (10%), of whom 6 had metastatic disease (3.5%).CONCLUSIONS: Routine use of chest CT in diagnostic workup for pancreatic head carcinoma reveals clinically significant lesions in 10% of patients, being metastases in up to 4%.",

keywords = "multiple pulmonary nodules, pancreas, pancreatic neoplasms, solitary pulmonary nodule, x-ray computed tomography",

author = "Dianne Leeuw and Pranger, {Bobby K} and {de Jong}, {Koert P} and Pennings, {Jan Pieter} and {de Meijer}, {Vincent E} and Erdmann, {Joris I}",

year = "2020",

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doi = "https://doi.org/10.1097/MPA.0000000000001494",

language = "English",

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T1 - Routine Chest Computed Tomography for Staging of Pancreatic Head Carcinoma

AU - Leeuw, Dianne

AU - Pranger, Bobby K

AU - de Jong, Koert P

AU - Pennings, Jan Pieter

AU - de Meijer, Vincent E

AU - Erdmann, Joris I

PY - 2020/3/1

Y1 - 2020/3/1

N2 - OBJECTIVES: The diagnostic value of routine chest computed tomography (CT) in addition to abdominal CT in workup for pancreatic head carcinoma is unclear. The aim of this study was to determine if routine chest CT revealed significant lesions that altered the management of patients with suspected pancreatic head carcinoma.METHODS: All Dutch pancreatic cancer centers were surveyed on the use of chest CT in preoperative staging. In addition, a single-center retrospective cohort study was performed including all patients referred with suspected pancreatic head malignancy without chest CT between 2005 and 2016. The primary end point was the proportion of patients in which chest CT revealed clinically significant lesions, leading to a change in management.RESULTS: In 7 of 18 Dutch pancreatic cancer centers (39%), a preoperative chest CT is not routinely performed. In the study cohort, 170 of 848 patients (20%) were referred without chest CT and underwent one by local protocol. Chest CT revealed new suspicious lesions in 17 patients (10%), of whom 6 had metastatic disease (3.5%).CONCLUSIONS: Routine use of chest CT in diagnostic workup for pancreatic head carcinoma reveals clinically significant lesions in 10% of patients, being metastases in up to 4%.

AB - OBJECTIVES: The diagnostic value of routine chest computed tomography (CT) in addition to abdominal CT in workup for pancreatic head carcinoma is unclear. The aim of this study was to determine if routine chest CT revealed significant lesions that altered the management of patients with suspected pancreatic head carcinoma.METHODS: All Dutch pancreatic cancer centers were surveyed on the use of chest CT in preoperative staging. In addition, a single-center retrospective cohort study was performed including all patients referred with suspected pancreatic head malignancy without chest CT between 2005 and 2016. The primary end point was the proportion of patients in which chest CT revealed clinically significant lesions, leading to a change in management.RESULTS: In 7 of 18 Dutch pancreatic cancer centers (39%), a preoperative chest CT is not routinely performed. In the study cohort, 170 of 848 patients (20%) were referred without chest CT and underwent one by local protocol. Chest CT revealed new suspicious lesions in 17 patients (10%), of whom 6 had metastatic disease (3.5%).CONCLUSIONS: Routine use of chest CT in diagnostic workup for pancreatic head carcinoma reveals clinically significant lesions in 10% of patients, being metastases in up to 4%.

KW - multiple pulmonary nodules

KW - pancreas

KW - pancreatic neoplasms

KW - solitary pulmonary nodule

KW - x-ray computed tomography

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Routine Chest Computed Tomography for Staging of Pancreatic Head Carcinoma

Abstract

Keywords

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