Serous retinal detachment as an early presentation of thrombotic thrombocytopenic purpura

Prabath Nanayakkara, Reinold O B Gans, José Reichert-Thoen, Pieter M. Ter Wee

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7 Citations (Scopus)


A 23-year-old woman presented with abdominal pain and blurred vision in both eyes. Fundoscopy revealed large bullous detachments of her neurosensory retina with shifting subretinal fluids bilaterally. Laboratory studies showed a hemoglobin of 6.5 mmol/l, thrombocytes 20 x 10 9/l, and LDH 1098 U/l. A peripheral blood smear revealed red blood cell fragmentation. A diagnosis of thrombotic thrombocytopenic purpura was made. The patient was treated with four sessions of plasmapheresis followed by plasma infusions, which resulted in a complete recovery. (C) 2000 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)286-288
Number of pages3
JournalEuropean Journal of Internal Medicine
Issue number5
Publication statusPublished - 1 Oct 2000


  • Blurred vision
  • Retinal detachment
  • Thrombotic thrombocytopenic purpura

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