TY - JOUR
T1 - Short-term patterns of pulsatile luteinizing hormone secretion do not differ between male-to-female transsexuals and heterosexual men
AU - Spijkstra, J. J.
AU - Spinder, T.
AU - Gooren, L. J.G.
PY - 1988/1/1
Y1 - 1988/1/1
N2 - This study tested whether there is a difference in the pulsatile LH secretion between male-to-female transsexuals and eugonadal heterosexual men. The mean serum LH concentrations, the LH pulse frequency, and the LH pulse amplitude were compared between a group of eight male-to-female transsexuals and a group of 22 heterosexual men. Blood samples for LH determinations were collected every 10 min for seven hours. 17-β-estradiol and testosterone were measured at the beginning of each test. There were no significant differences between the heterosexual and transsexual group in LH pulse frequency (3.9±1.3 vs. 3.9±1.7), LH pulse amplitude (3.7±1.3 U/l vs. 3.0±0.5 U/l), mean serum LH concentration (5.2±1.4 U/l vs. 5.4±1.1 U/l), 17-β-estradiol (0.07±0.01 nmol/l vs. 0.08±0.02 nmol/l), or testosterone (22.9±3.7 nmol/l vs. 21.8±8.0 nmol/l). We conclude that the pulsatile release characteristics of LH do not allow a distinction between eugonadal heterosexual men and eugonadal male-to-female transsexuals.
AB - This study tested whether there is a difference in the pulsatile LH secretion between male-to-female transsexuals and eugonadal heterosexual men. The mean serum LH concentrations, the LH pulse frequency, and the LH pulse amplitude were compared between a group of eight male-to-female transsexuals and a group of 22 heterosexual men. Blood samples for LH determinations were collected every 10 min for seven hours. 17-β-estradiol and testosterone were measured at the beginning of each test. There were no significant differences between the heterosexual and transsexual group in LH pulse frequency (3.9±1.3 vs. 3.9±1.7), LH pulse amplitude (3.7±1.3 U/l vs. 3.0±0.5 U/l), mean serum LH concentration (5.2±1.4 U/l vs. 5.4±1.1 U/l), 17-β-estradiol (0.07±0.01 nmol/l vs. 0.08±0.02 nmol/l), or testosterone (22.9±3.7 nmol/l vs. 21.8±8.0 nmol/l). We conclude that the pulsatile release characteristics of LH do not allow a distinction between eugonadal heterosexual men and eugonadal male-to-female transsexuals.
UR - http://www.scopus.com/inward/record.url?scp=0023889227&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/0306-4530(88)90026-1
DO - https://doi.org/10.1016/0306-4530(88)90026-1
M3 - Article
C2 - 3406325
SN - 0306-4530
VL - 13
SP - 279
EP - 283
JO - Psychoneuroendocrinology
JF - Psychoneuroendocrinology
IS - 3
ER -