@article{5cd0959d6f94493d972cbd69e89f8ca2,
title = "Should we continue surveillance for hepatocellular carcinoma and gastroesophageal varices in patients with cirrhosis and cured HCV infection?",
abstract = "Hepatocellular carcinoma (HCC) and variceal bleeding are among the most common causes of liver-related mortality in patients with hepatitis C virus (HCV)-induced cirrhosis. Current guidelines recommend HCC and gastroesophageal varices (GEV) surveillance in patients with HCV infection and cirrhosis. However, since the recent introduction of direct-acting antivirals, most patients with cirrhosis are now cured of their chronic HCV infection. As virological cure is considered to substantially reduce the risk of cirrhosis-related complications, this review discusses the current literature concerning the surveillance of HCC and GEV in patients with HCV-induced cirrhosis with a focus on the setting following sustained virological response.",
keywords = "Cirrhosis, Direct-acting antivirals, Hepatitis C, Surveillance, Variceal bleeding, Viral hepatitis",
author = "Isfordink, {Cas J.} and Raoel Maan and {de Man}, {Robert A.} and {van Erpecum}, {Karel J.} and {van der Meer}, {Adriaan J.}",
note = "Funding Information: Cas J Isfordink follows a PhD traject in the CELINE (hepatitis C elimination in the Netherlands) initiative sponsored by Gilead. Raoel Maan received financial compensation for consultancy from AbbVie. Robert A de Man has nothing to disclose. Karel J van Erpecum participated in advisory boards of Gilead, Janssen-Cilag, BMS, Abbvie, and MSD and received research grants from Gilead, Janssen-Cilag and the DutchCancer Society (KWF Kankerbestrijding). Adriaan J van der Meer received financial compensation for lecture activities from Zambon, research funding from Gilead, MSD, AbbVie and Zambon, and compensation for consultancy from AOP Orphan. Publisher Copyright: {\textcopyright} 2021",
year = "2021",
month = dec,
doi = "https://doi.org/10.1016/j.ejim.2021.08.023",
language = "English",
volume = "94",
pages = "6--14",
journal = "European Journal of Internal Medicine",
issn = "0953-6205",
publisher = "Elsevier",
}