TY - JOUR
T1 - Skin Toxicity of Selected Hair Cosmetic Ingredients
T2 - A Review Focusing on Hairdressers
AU - Symanzik, Cara
AU - Weinert, Patricia
AU - Babić, Željka
AU - Hallmann, Sarah
AU - Havmose, Martin Stibius
AU - Johansen, Jeanne Duus
AU - Kezic, Sanja
AU - Macan, Marija
AU - Macan, Jelena
AU - Strahwald, Julia
AU - Turk, Rajka
AU - van der Molen, Henk F.
AU - John, Swen Malte
AU - Uter, Wolfgang
N1 - Funding Information: Funding: This systematic review is supported by a grant from Uni Europa–The European Global Services Union (Project VS/2019/0440: “Promoting the autonomous implementation of the European framework agreement on occupational health and safety in the hairdressing sector”). Other than being given the opportunity to provide input to the initial Delphi process to identify relevant substances, the sponsor had no role in the development or in the performance of the systematic review and the publication of its results. Funding Information: Acknowledgments: The authors would like to thank the European Commission, Directorate General Employment, Social Affairs and Inclusion (VS/2019/0440) for their financial support. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/7/1
Y1 - 2022/7/1
N2 - The safety assessment of cosmetics considers the exposure of a ‘common consumer’, not the occupational exposure of hairdressers. This review aims to compile and appraise evidence regarding the skin toxicity of cysteamine hydrochloride (cysteamine HCl; CAS no. 156-57-0), polyvi-nylpyrrolidone (PVP; CAS no. 9003-39-8), PVP copolymers (CAS no. 28211-18-9), sodium laureth sulfate (SLES; CAS no. 9004-82-4), cocamide diethanolamine (cocamide DEA; CAS no. 68603-42-9), and cocamidopropyl betaine (CAPB; CAS no. 61789-40-0). A total of 298 articles were identified, of which 70 were included. Meta-analysis revealed that hairdressers have a 1.7-fold increased risk of developing a contact allergy to CAPB compared to controls who are not hairdressers. Hairdressers might have a higher risk of acquiring quantum sensitization against cysteamine HCl compared to a consumer because of their job responsibilities. Regarding cocamide DEA, the irritant potential of this surfactant should not be overlooked. Original articles for PVP, PVP copolymers, and SLES are lacking. This systematic review indicates that the current standards do not effectively address the occupational risks associated with hairdressers’ usage of hair cosmetics. The considerable irritant and/or allergenic potential of substances used in hair cosmetics should prompt a reassessment of current risk assessment practices.
AB - The safety assessment of cosmetics considers the exposure of a ‘common consumer’, not the occupational exposure of hairdressers. This review aims to compile and appraise evidence regarding the skin toxicity of cysteamine hydrochloride (cysteamine HCl; CAS no. 156-57-0), polyvi-nylpyrrolidone (PVP; CAS no. 9003-39-8), PVP copolymers (CAS no. 28211-18-9), sodium laureth sulfate (SLES; CAS no. 9004-82-4), cocamide diethanolamine (cocamide DEA; CAS no. 68603-42-9), and cocamidopropyl betaine (CAPB; CAS no. 61789-40-0). A total of 298 articles were identified, of which 70 were included. Meta-analysis revealed that hairdressers have a 1.7-fold increased risk of developing a contact allergy to CAPB compared to controls who are not hairdressers. Hairdressers might have a higher risk of acquiring quantum sensitization against cysteamine HCl compared to a consumer because of their job responsibilities. Regarding cocamide DEA, the irritant potential of this surfactant should not be overlooked. Original articles for PVP, PVP copolymers, and SLES are lacking. This systematic review indicates that the current standards do not effectively address the occupational risks associated with hairdressers’ usage of hair cosmetics. The considerable irritant and/or allergenic potential of substances used in hair cosmetics should prompt a reassessment of current risk assessment practices.
KW - cocamide diethanolamine
KW - cocamidopropyl betaine
KW - cosmet-ics
KW - cysteamine hydrochloride
KW - hairdresser
KW - hairdressing
KW - hand eczema
KW - polyvinylpyrrolidone
KW - polyvinylpyrrolidone copoly-mers
KW - sodium laureth sulfate
UR - http://www.scopus.com/inward/record.url?scp=85132278883&partnerID=8YFLogxK
U2 - https://doi.org/10.3390/ijerph19137588
DO - https://doi.org/10.3390/ijerph19137588
M3 - Review article
C2 - 35805241
SN - 1661-7827
VL - 19
JO - International journal of environmental research and public health
JF - International journal of environmental research and public health
IS - 13
M1 - 7588
ER -