Sleep benefits subsequent hippocampal functioning

Y.D. van der Werf, E. Altena, M.M. Schoonheim, E.J. Sanz-Arigita, J.C. Vis, W. de Rijke, E.J. van Someren

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237 Citations (Scopus)


Sleep before learning benefits memory encoding through unknown mechanisms. We found that even a mild sleep disruption that suppressed slow-wave activity and induced shallow sleep, but did not reduce total sleep time, was sufficient to affect subsequent successful encoding-related hippocampal activation and memory performance in healthy human subjects. Implicit learning was not affected. Our results suggest that the hippocampus is particularly sensitive to shallow, but intact, sleep. © 2009 Nature America, Inc. All rights reserved.
Original languageEnglish
Pages (from-to)122-123
JournalNature neuroscience
Issue number2
Publication statusPublished - 2009

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