TY - JOUR
T1 - Social variables predict gains in cognitive scores across the preschool years in children with birth weights 500 to 1250 grams
AU - Manley, Brett J.
AU - Roberts, Robin S.
AU - Doyle, Lex W.
AU - Schmidt, Barbara
AU - Anderson, Peter J.
AU - Barrington, Keith J.
AU - Böhm, Birgitta
AU - Golan, Agneta
AU - van Wassenaer-Leemhuis, Aleid G.
AU - Davis, Peter G.
AU - AUTHOR GROUP
AU - D'Ilario, Judy
AU - Cairnie, Janice
AU - Dix, Joanne
AU - Adams, Beth Anne
AU - Warriner, Erin
AU - Kim, Mee-Hai Marie
AU - Anderson, Peter
AU - Davis, Peter
AU - Doyle, Lex
AU - Argus, Brenda
AU - Callanan, Catherine
AU - Davis, Noni
AU - Duff, Julianne
AU - McDonald, Marion
AU - Asztalos, Elizabeth
AU - Hohn, Denise
AU - Lacy, Maralyn
AU - Haslam, Ross
AU - Barnett, Christopher
AU - Goodchild, Louise
AU - Lontis, Rosslyn Marie
AU - Fraser, Simon
AU - Keng, Julie
AU - Saunders, Kerryn
AU - Opie, Gillian
AU - Kelly, Elaine
AU - Woods, Heather
AU - Marchant, Emma
AU - Turner, Anne-Marie
AU - Magrath, Emma
AU - Williamson, Amanda
AU - Bairam, Aida
AU - Bélanger, Sylvie
AU - Fraser, Annie
AU - Blayney, Marc
AU - Lemyre, Brigitte
AU - Frank, Jane
AU - Solimano, Alfonso
AU - Houtzager, Bregje
AU - van Sonderen, Loekie
PY - 2015
Y1 - 2015
N2 - To determine the extent that social variables influence cognitive development of very low birth weight (VLBW) infants across the preschool years. Participants were VLBW (500-1250 g) children enrolled in the Caffeine for Apnea of Prematurity randomized trial between 1999 and 2004. We investigated the relationships between 4 potential social advantages: higher maternal education, higher paternal education, caregiver employment, and 2 biologic parents in the same home--and gain in cognitive scores. Cognitive assessments were performed at the corrected ages of 18 months (Mental Development Index score on the Bayley Scales of Infant Development II) and 5 years (Full Scale IQ on the Wechsler Preschool and Primary Scale of Intelligence III). Cognitive gain was computed by subtracting each individual 18-month Mental Development Index score from the corresponding Full Scale IQ at 5 years. Data were available for 1347 children. Mean (SD) cognitive scores were 90.8 (15.7) at 18 months and 98.9 (14.5) at 5 years. Multivariable regression showed that higher maternal education, higher paternal education, and caregiver employment had independent and additive effects of similar size on cognitive gain (P < .001); the mean cognitive gain between 18 months and 5 years increased by 3.6 points in the presence of each of these advantages. When all 3 were present, cognitive scores improved on average by 10.9 points compared with children without any of these advantages. In VLBW children, a count of 3 social advantages strongly predicts gains in cognitive scores across the preschool years
AB - To determine the extent that social variables influence cognitive development of very low birth weight (VLBW) infants across the preschool years. Participants were VLBW (500-1250 g) children enrolled in the Caffeine for Apnea of Prematurity randomized trial between 1999 and 2004. We investigated the relationships between 4 potential social advantages: higher maternal education, higher paternal education, caregiver employment, and 2 biologic parents in the same home--and gain in cognitive scores. Cognitive assessments were performed at the corrected ages of 18 months (Mental Development Index score on the Bayley Scales of Infant Development II) and 5 years (Full Scale IQ on the Wechsler Preschool and Primary Scale of Intelligence III). Cognitive gain was computed by subtracting each individual 18-month Mental Development Index score from the corresponding Full Scale IQ at 5 years. Data were available for 1347 children. Mean (SD) cognitive scores were 90.8 (15.7) at 18 months and 98.9 (14.5) at 5 years. Multivariable regression showed that higher maternal education, higher paternal education, and caregiver employment had independent and additive effects of similar size on cognitive gain (P < .001); the mean cognitive gain between 18 months and 5 years increased by 3.6 points in the presence of each of these advantages. When all 3 were present, cognitive scores improved on average by 10.9 points compared with children without any of these advantages. In VLBW children, a count of 3 social advantages strongly predicts gains in cognitive scores across the preschool years
U2 - https://doi.org/10.1016/j.jpeds.2014.12.016
DO - https://doi.org/10.1016/j.jpeds.2014.12.016
M3 - Article
C2 - 25641237
SN - 0022-3476
VL - 166
SP - 870-6.e1-2
JO - Journal of pediatrics
JF - Journal of pediatrics
IS - 4
ER -