Spatial distributions of optical and acoustic properties and correlations with temperature in cyclically frozen-thawed poly(vinyl alcohol) gel breast phantoms

Daniele Piras, Wenfeng Xia, Michelle Heijblom, Wiendelt Steenbergen, Ton G. Van Leeuwen, Srirang Manohar

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

2 Citations (Scopus)

Abstract

Tissue mimicking phantoms are important for performance evaluation of imaging systems: in photoacoustics they need to accomplish both soft tissue optical and acoustic properties. PVA gels by freezing-thawing (F-T) have been used to simulate tissue properties. The microstructure, dependent on rate and extent of temperature cycling, is responsible for optical and acoustic properties. In F-T of larger phantoms, temperature differences in the mass are expected, resulting in a likely inhomogeneous distribution of properties in the phantom. We investigated speed of sound, acoustic attenuation, reduced optical scattering coefficient and microstructure: their variations are correlated with thermal differences between phantom surface and bulk.

Original languageEnglish
Title of host publicationOptical Diagnostics and Sensing XI
Subtitle of host publicationToward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue III
DOIs
Publication statusPublished - 2011
EventOptical Diagnostics and Sensing XI: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue III - San Francisco, CA, United States
Duration: 22 Jan 201126 Jan 2011

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7906

Conference

ConferenceOptical Diagnostics and Sensing XI: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue III
Country/TerritoryUnited States
CitySan Francisco, CA
Period22/01/201126/01/2011

Keywords

  • PVA
  • Phantoms
  • Photoacoustic
  • Pores

Cite this