TY - CHAP
T1 - Stem cells
T2 - sources, properties, and cell types
AU - Asal, Melis
AU - Asal, Melis
AU - Güven, Sinan
AU - Güven, Sinan
AU - Güven, Sinan
AU - Güven, Sinan
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Tissue engineering applications hold the promise to restore, repair, and improve tissue function either through in vivo cellular therapy or by the use of in vitro developed tissue constructs. The biggest burden of the field limiting its clinical applications is the scarce number of cell sources. Stem cells, with their self-renewal and differentiation capacities, serve as an excellent cell source for tissue engineering applications. To search for stem cells with suitable differentiation capacities and inducing their differentiation to certain lineages is critical. Biomaterials with tailored properties offer microenvironments capable of controlling stem cell behavior by mimicking the stem cell niche. In this chapter, we explain the importance of stem cells in tissue engineering by covering their self-renewal and differentiation properties, we summarize the types of stem cells, their sources and offer some examples from the recent literature that employ stem cells to generate various tissues.
AB - Tissue engineering applications hold the promise to restore, repair, and improve tissue function either through in vivo cellular therapy or by the use of in vitro developed tissue constructs. The biggest burden of the field limiting its clinical applications is the scarce number of cell sources. Stem cells, with their self-renewal and differentiation capacities, serve as an excellent cell source for tissue engineering applications. To search for stem cells with suitable differentiation capacities and inducing their differentiation to certain lineages is critical. Biomaterials with tailored properties offer microenvironments capable of controlling stem cell behavior by mimicking the stem cell niche. In this chapter, we explain the importance of stem cells in tissue engineering by covering their self-renewal and differentiation properties, we summarize the types of stem cells, their sources and offer some examples from the recent literature that employ stem cells to generate various tissues.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85125414885&origin=inward
U2 - https://doi.org/10.1016/B978-0-08-102906-0.00007-6
DO - https://doi.org/10.1016/B978-0-08-102906-0.00007-6
M3 - Chapter
SN - 9780081029077
T3 - Biomaterials for Organ and Tissue Regeneration: New Technologies and Future Prospects
SP - 177
EP - 196
BT - Biomaterials for Organ and Tissue Regeneration: New Technologies and Future Prospects
PB - Elsevier
ER -