TY - JOUR
T1 - Stereotactic Radiosurgery in the Management of Brain Metastases
T2 - A Case-Based Radiosurgery Society Practice Guideline
AU - Ladbury, Colton
AU - Pennock, Michael
AU - Yilmaz, Tugba
AU - Ankrah, Nii-Kwanchie
AU - Andraos, Therese
AU - Gogineni, Emile
AU - Kim, Grace Gwe-Ya
AU - Gibbs, Iris
AU - Shih, Helen A.
AU - Hattangadi-Gluth, Jona
AU - Chao, Samuel T.
AU - Pannullo, Susan C.
AU - Slotman, Ben
AU - Redmond, Kristin J.
AU - Lo, Simon S.
AU - Schulder, Michael
N1 - Publisher Copyright: © 2023
PY - 2024/3/1
Y1 - 2024/3/1
N2 - Purpose: Brain metastases are common among adult patients with solid malignancies and are increasingly being treated with stereotactic radiosurgery (SRS). As more patients with brain metastases are becoming eligible for SRS, there is a need for practical review of patient selection and treatment considerations. Methods and Materials: Two patient cases were identified to use as the foundation for a discussion of a wide and representative range of management principles: (A) SRS alone for 5 to 15 lesions and (B) a large single metastasis to be treated with pre- or postoperative SRS. Patient selection, fractionation, prescription dose, treatment technique, and dose constraints are discussed. Literature relevant to these cases is summarized to provide a framework for treatment of similar patients. Results: Treatment of brain metastases with SRS requires many considerations including optimal patient selection, fractionation selection, and plan optimization. Conclusions: Case-based practice guidelines developed by the Radiosurgery Society provide a practical guide to the common scenarios noted above affecting patients with metastatic brain tumors.
AB - Purpose: Brain metastases are common among adult patients with solid malignancies and are increasingly being treated with stereotactic radiosurgery (SRS). As more patients with brain metastases are becoming eligible for SRS, there is a need for practical review of patient selection and treatment considerations. Methods and Materials: Two patient cases were identified to use as the foundation for a discussion of a wide and representative range of management principles: (A) SRS alone for 5 to 15 lesions and (B) a large single metastasis to be treated with pre- or postoperative SRS. Patient selection, fractionation, prescription dose, treatment technique, and dose constraints are discussed. Literature relevant to these cases is summarized to provide a framework for treatment of similar patients. Results: Treatment of brain metastases with SRS requires many considerations including optimal patient selection, fractionation selection, and plan optimization. Conclusions: Case-based practice guidelines developed by the Radiosurgery Society provide a practical guide to the common scenarios noted above affecting patients with metastatic brain tumors.
UR - http://www.scopus.com/inward/record.url?scp=85182578617&partnerID=8YFLogxK
U2 - 10.1016/j.adro.2023.101402
DO - 10.1016/j.adro.2023.101402
M3 - Review article
C2 - 38292892
SN - 2452-1094
VL - 9
JO - Advances in Radiation Oncology
JF - Advances in Radiation Oncology
IS - 3
M1 - 101402
ER -