TY - JOUR
T1 - Stress-reducing interventions in pregnancy for the prevention of preterm birth
T2 - a systematic review and meta-analysis
AU - Janssen, Laura E.
AU - Gieskes, Adelia A.
AU - Kok, Marjolein
AU - de Groot, Christianne J. M.
AU - Oudijk, Martijn A.
AU - de Boer, Marjon A.
PY - 2023
Y1 - 2023
N2 - Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality. Maternal stress during pregnancy is an established risk factor for PTB. We aimed to review the effects of stress-reducing interventions during pregnancy on PTB. Studies reporting on stress-reducing interventions during pregnancy and PTB rates in general low-risk obstetric populations were included. PTB rates, low birth weight (LBW) rates, mean gestational age and birth weight, maternal anxiety and stress, and adverse perinatal outcomes were investigated. Data were extracted using a standardized extraction form, pooled effect sizes were calculated with the random effects model. Ten studies with a total of 4.816 women were included. The interventions included Pilates, yoga, a multidisciplinary stress reduction program, combination therapy (combining mindfulness, yoga, music, baby bonding, and education), and hypnosis. The incidence of PTB was significantly lower in the intervention group (RR 0.50, 95% CI 0.35 − 0.71). The overall quality of the included studies was low, and the risk of bias was high. In conclusion, this study provides evidence supporting the potential efficacy of stress-reducing interventions in reducing the incidence of PTB in low-risk women. We propose a RCT of high quality to determine the effectiveness of stress-reducing interventions in reducing PTB risk.
AB - Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality. Maternal stress during pregnancy is an established risk factor for PTB. We aimed to review the effects of stress-reducing interventions during pregnancy on PTB. Studies reporting on stress-reducing interventions during pregnancy and PTB rates in general low-risk obstetric populations were included. PTB rates, low birth weight (LBW) rates, mean gestational age and birth weight, maternal anxiety and stress, and adverse perinatal outcomes were investigated. Data were extracted using a standardized extraction form, pooled effect sizes were calculated with the random effects model. Ten studies with a total of 4.816 women were included. The interventions included Pilates, yoga, a multidisciplinary stress reduction program, combination therapy (combining mindfulness, yoga, music, baby bonding, and education), and hypnosis. The incidence of PTB was significantly lower in the intervention group (RR 0.50, 95% CI 0.35 − 0.71). The overall quality of the included studies was low, and the risk of bias was high. In conclusion, this study provides evidence supporting the potential efficacy of stress-reducing interventions in reducing the incidence of PTB in low-risk women. We propose a RCT of high quality to determine the effectiveness of stress-reducing interventions in reducing PTB risk.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85179649542&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/38064297
U2 - 10.1080/0167482X.2023.2281238
DO - 10.1080/0167482X.2023.2281238
M3 - Review article
C2 - 38064297
SN - 0167-482X
VL - 44
JO - Journal of Psychosomatic Obstetrics and Gynecology
JF - Journal of Psychosomatic Obstetrics and Gynecology
IS - 1
M1 - 2281238
ER -