Subfertile men with constitutive chromosome abnormalities do not necessarily refrain from intracytoplasmic sperm injection treatment: a follow-up study on 75 Dutch patients

J. C. Giltay; P. M. Kastrop; J. H. Tuerlings; J. A. Kremer; C. H. Tiemessen; K. B. Gerssen-Schoorl; F. van der Veen; J. de Vries; R. Hordijk; G. J. Hamers; K. Hansson; M. van der Blij-Philipsen; L. C. Govaerts; M. H. Pieters; K. Madan; J. M. Scheres

doi:https://doi.org/10.1093/humrep/14.2.318

Subfertile men with constitutive chromosome abnormalities do not necessarily refrain from intracytoplasmic sperm injection treatment: a follow-up study on 75 Dutch patients

J. C. Giltay, P. M. Kastrop, J. H. Tuerlings, J. A. Kremer, C. H. Tiemessen, K. B. Gerssen-Schoorl, F. van der Veen, J. de Vries, R. Hordijk, G. J. Hamers, K. Hansson, M. van der Blij-Philipsen, L. C. Govaerts, M. H. Pieters, K. Madan, J. M. Scheres

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Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

A follow-up study was performed to investigate the impact of the detection of a chromosome abnormality in infertile men who are candidates for intracytoplasmic sperm injection (ICSI) treatment. In this collaborative study between clinical genetics centres and fertility clinics in the Netherlands, 75 ICSI couples of which the male partners had a chromosome abnormality were included. All couples were extensively counselled on the risk of having a chromosomally unbalanced child. Forty-two out of 75 couples chose to proceed with the ICSI treatment. So far, treatment has resulted in a pregnancy in 11 cases. Four of them opted to have invasive prenatal diagnosis. Despite the genetic risks related to a chromosome abnormality in infertile men, a small majority (56%) of the couples did not refrain from the ICSI treatment

Original language	English
Pages (from-to)	318-320
Journal	Human reproduction (Oxford, England)
Volume	14
Issue number	2
DOIs	https://doi.org/10.1093/humrep/14.2.318
Publication status	Published - 1999

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https://doi.org/10.1093/humrep/14.2.318

Cite this

Giltay, J. C., Kastrop, P. M., Tuerlings, J. H., Kremer, J. A., Tiemessen, C. H., Gerssen-Schoorl, K. B., van der Veen, F., de Vries, J., Hordijk, R., Hamers, G. J., Hansson, K., van der Blij-Philipsen, M., Govaerts, L. C., Pieters, M. H., Madan, K., & Scheres, J. M. (1999). Subfertile men with constitutive chromosome abnormalities do not necessarily refrain from intracytoplasmic sperm injection treatment: a follow-up study on 75 Dutch patients. Human reproduction (Oxford, England), 14(2), 318-320. https://doi.org/10.1093/humrep/14.2.318

@article{ea6ee7cbb430472c8dd04e6a6e0d7aec,

title = "Subfertile men with constitutive chromosome abnormalities do not necessarily refrain from intracytoplasmic sperm injection treatment: a follow-up study on 75 Dutch patients",

abstract = "A follow-up study was performed to investigate the impact of the detection of a chromosome abnormality in infertile men who are candidates for intracytoplasmic sperm injection (ICSI) treatment. In this collaborative study between clinical genetics centres and fertility clinics in the Netherlands, 75 ICSI couples of which the male partners had a chromosome abnormality were included. All couples were extensively counselled on the risk of having a chromosomally unbalanced child. Forty-two out of 75 couples chose to proceed with the ICSI treatment. So far, treatment has resulted in a pregnancy in 11 cases. Four of them opted to have invasive prenatal diagnosis. Despite the genetic risks related to a chromosome abnormality in infertile men, a small majority (56%) of the couples did not refrain from the ICSI treatment",

author = "Giltay, {J. C.} and Kastrop, {P. M.} and Tuerlings, {J. H.} and Kremer, {J. A.} and Tiemessen, {C. H.} and Gerssen-Schoorl, {K. B.} and {van der Veen}, F. and {de Vries}, J. and R. Hordijk and Hamers, {G. J.} and K. Hansson and {van der Blij-Philipsen}, M. and Govaerts, {L. C.} and Pieters, {M. H.} and K. Madan and Scheres, {J. M.}",

year = "1999",

doi = "https://doi.org/10.1093/humrep/14.2.318",

language = "English",

volume = "14",

pages = "318--320",

journal = "Human reproduction (Oxford, England)",

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Giltay, JC, Kastrop, PM, Tuerlings, JH, Kremer, JA, Tiemessen, CH, Gerssen-Schoorl, KB, van der Veen, F, de Vries, J, Hordijk, R, Hamers, GJ, Hansson, K, van der Blij-Philipsen, M, Govaerts, LC, Pieters, MH, Madan, K & Scheres, JM 1999, 'Subfertile men with constitutive chromosome abnormalities do not necessarily refrain from intracytoplasmic sperm injection treatment: a follow-up study on 75 Dutch patients', Human reproduction (Oxford, England), vol. 14, no. 2, pp. 318-320. https://doi.org/10.1093/humrep/14.2.318

Subfertile men with constitutive chromosome abnormalities do not necessarily refrain from intracytoplasmic sperm injection treatment: a follow-up study on 75 Dutch patients. / Giltay, J. C.; Kastrop, P. M.; Tuerlings, J. H. et al.
In: Human reproduction (Oxford, England), Vol. 14, No. 2, 1999, p. 318-320.

Research output: Contribution to journal › Article › Academic › peer-review

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