Subklinische hyperthyreoïdie; start van klinische trial naar het nut van behandeling met radioactief jood

E. H. Hoogendoorn; W. M. Wiersinga; M. F. Prummel; M. Den Heijer; F. H. Corstens; A. R. Hermus

Subklinische hyperthyreoïdie; start van klinische trial naar het nut van behandeling met radioactief jood

Translated title of the contribution: Subclinical hyperthyroidism; the start of a clinical trial into the usefulness of treatment with radioactive iodine

E. H. Hoogendoorn, W. M. Wiersinga, M. F. Prummel, M. Den Heijer, F. H. Corstens, A. R. Hermus

Research output: Contribution to journal › Article › Academic › peer-review

4 Citations (Scopus)

Abstract

Subclinical hyperthyroidism is defined as the presence of serum free thyroxine (T₄) and triiodothyronine (T₃) levels within the reference range and a reduced serum thyrotrophin (TSH) level. Evidence is accumulating that it has important clinical effects. Randomised clinical trials are needed to answer the question whether or not treatment of subclinical hyperthyroidism prevents cardiac problems, especially atrial fibrillation, and preserves bone mineral density. A randomised, Dutch multicentre trial has recently been started. Its goal is to study whether radioiodine treatment prevents the development of atrial fibrillation and prevents decreases in bone mineral density.

Translated title of the contribution	Subclinical hyperthyroidism; the start of a clinical trial into the usefulness of treatment with radioactive iodine
Original language	Dutch
Pages (from-to)	953-954
Number of pages	2
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	148
Issue number	19
Publication status	Published - 8 May 2004

Cite this

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AU - Hoogendoorn, E. H.

AU - Wiersinga, W. M.

AU - Prummel, M. F.

AU - Den Heijer, M.

AU - Corstens, F. H.

AU - Hermus, A. R.

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AB - Subclinical hyperthyroidism is defined as the presence of serum free thyroxine (T4) and triiodothyronine (T3) levels within the reference range and a reduced serum thyrotrophin (TSH) level. Evidence is accumulating that it has important clinical effects. Randomised clinical trials are needed to answer the question whether or not treatment of subclinical hyperthyroidism prevents cardiac problems, especially atrial fibrillation, and preserves bone mineral density. A randomised, Dutch multicentre trial has recently been started. Its goal is to study whether radioiodine treatment prevents the development of atrial fibrillation and prevents decreases in bone mineral density.

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ER -

Subklinische hyperthyreoïdie; start van klinische trial naar het nut van behandeling met radioactief jood

Abstract

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