Systematic review: accuracy of imaging tests in the diagnosis of recurrent laryngeal carcinoma after radiotherapy

Jolijn Brouwer; Lotty Hooft; Otto S. Hoekstra; Ingrid I. Riphagen; Jonas A. Castelijns; Remco de Bree; C. René Leemans

doi:https://doi.org/10.1002/hed.20790

Systematic review: accuracy of imaging tests in the diagnosis of recurrent laryngeal carcinoma after radiotherapy

Jolijn Brouwer, Lotty Hooft, Otto S. Hoekstra, Ingrid I. Riphagen, Jonas A. Castelijns, Remco de Bree, C. René Leemans

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

BACKGROUND: Diagnosing recurrent laryngeal tumor after radiotherapy is challenging. The most reliable method is direct laryngoscopy under general anesthesia. However, many futile laryngoscopies are performed in disease-free patients. Imaging tests selecting patients for this invasive procedure would be useful. The aim of this systematic review was summarizing the available evidence and determining the diagnostic accuracy of CT, MRI, thallium-201 (201Tl) scintigraphy, and F-18-fluorodeoxyglucose positron emission tomography (18FDG-PET). METHODS: A systematic review was performed according to the guidelines of the Cochrane Collaboration. Two reviewers scored the articles according to A-, B-, and C-items. Statistical meta-analysis was performed producing summary pooled estimates of sensitivity and specificity. RESULTS: There were 8 eligible studies on 18FDG-PET. The validity of the 18FDG-PET studies was reasonable; the pooled estimates (95% CI) for sensitivity and specificity were 89% and 74%. CONCLUSION: The diagnostic accuracy of 18FDG-PET is promising and warrants a randomized trial comparing a strategy based on conventional diagnostic work-up to one based on 18FDG-PET

Original language	English
Pages (from-to)	889-897
Journal	Head & neck
Volume	30
Issue number	7
DOIs	https://doi.org/10.1002/hed.20790
Publication status	Published - 2008

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https://doi.org/10.1002/hed.20790

Cite this

@article{46b8c07e9e204f43a55c8c3708bbe6cd,

title = "Systematic review: accuracy of imaging tests in the diagnosis of recurrent laryngeal carcinoma after radiotherapy",

abstract = "BACKGROUND: Diagnosing recurrent laryngeal tumor after radiotherapy is challenging. The most reliable method is direct laryngoscopy under general anesthesia. However, many futile laryngoscopies are performed in disease-free patients. Imaging tests selecting patients for this invasive procedure would be useful. The aim of this systematic review was summarizing the available evidence and determining the diagnostic accuracy of CT, MRI, thallium-201 (201Tl) scintigraphy, and F-18-fluorodeoxyglucose positron emission tomography (18FDG-PET). METHODS: A systematic review was performed according to the guidelines of the Cochrane Collaboration. Two reviewers scored the articles according to A-, B-, and C-items. Statistical meta-analysis was performed producing summary pooled estimates of sensitivity and specificity. RESULTS: There were 8 eligible studies on 18FDG-PET. The validity of the 18FDG-PET studies was reasonable; the pooled estimates (95% CI) for sensitivity and specificity were 89% and 74%. CONCLUSION: The diagnostic accuracy of 18FDG-PET is promising and warrants a randomized trial comparing a strategy based on conventional diagnostic work-up to one based on 18FDG-PET",

author = "Jolijn Brouwer and Lotty Hooft and Hoekstra, {Otto S.} and Riphagen, {Ingrid I.} and Castelijns, {Jonas A.} and {de Bree}, Remco and Leemans, {C. Ren{\'e}}",

year = "2008",

doi = "https://doi.org/10.1002/hed.20790",

language = "English",

volume = "30",

pages = "889--897",

journal = "Head & neck",

issn = "1043-3074",

publisher = "John Wiley and Sons Inc.",

number = "7",

}

TY - JOUR

T1 - Systematic review: accuracy of imaging tests in the diagnosis of recurrent laryngeal carcinoma after radiotherapy

AU - Brouwer, Jolijn

AU - Hooft, Lotty

AU - Hoekstra, Otto S.

AU - Riphagen, Ingrid I.

AU - Castelijns, Jonas A.

AU - de Bree, Remco

AU - Leemans, C. René

PY - 2008

Y1 - 2008

N2 - BACKGROUND: Diagnosing recurrent laryngeal tumor after radiotherapy is challenging. The most reliable method is direct laryngoscopy under general anesthesia. However, many futile laryngoscopies are performed in disease-free patients. Imaging tests selecting patients for this invasive procedure would be useful. The aim of this systematic review was summarizing the available evidence and determining the diagnostic accuracy of CT, MRI, thallium-201 (201Tl) scintigraphy, and F-18-fluorodeoxyglucose positron emission tomography (18FDG-PET). METHODS: A systematic review was performed according to the guidelines of the Cochrane Collaboration. Two reviewers scored the articles according to A-, B-, and C-items. Statistical meta-analysis was performed producing summary pooled estimates of sensitivity and specificity. RESULTS: There were 8 eligible studies on 18FDG-PET. The validity of the 18FDG-PET studies was reasonable; the pooled estimates (95% CI) for sensitivity and specificity were 89% and 74%. CONCLUSION: The diagnostic accuracy of 18FDG-PET is promising and warrants a randomized trial comparing a strategy based on conventional diagnostic work-up to one based on 18FDG-PET

AB - BACKGROUND: Diagnosing recurrent laryngeal tumor after radiotherapy is challenging. The most reliable method is direct laryngoscopy under general anesthesia. However, many futile laryngoscopies are performed in disease-free patients. Imaging tests selecting patients for this invasive procedure would be useful. The aim of this systematic review was summarizing the available evidence and determining the diagnostic accuracy of CT, MRI, thallium-201 (201Tl) scintigraphy, and F-18-fluorodeoxyglucose positron emission tomography (18FDG-PET). METHODS: A systematic review was performed according to the guidelines of the Cochrane Collaboration. Two reviewers scored the articles according to A-, B-, and C-items. Statistical meta-analysis was performed producing summary pooled estimates of sensitivity and specificity. RESULTS: There were 8 eligible studies on 18FDG-PET. The validity of the 18FDG-PET studies was reasonable; the pooled estimates (95% CI) for sensitivity and specificity were 89% and 74%. CONCLUSION: The diagnostic accuracy of 18FDG-PET is promising and warrants a randomized trial comparing a strategy based on conventional diagnostic work-up to one based on 18FDG-PET

U2 - https://doi.org/10.1002/hed.20790

DO - https://doi.org/10.1002/hed.20790

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SN - 1043-3074

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JO - Head & neck

JF - Head & neck

IS - 7

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