TY - JOUR
T1 - Systolic Heart Failure: A Prothrombotic State
AU - de Peuter, Olav R.
AU - Kok, Wouter E. M.
AU - Torp-Pedersen, Christian
AU - Büller, Harry R.
AU - Kamphuisen, Pieter W.
PY - 2009
Y1 - 2009
N2 - Systolic heart failure is a common syndrome whose Incidence is expected to increase. Several treatment modalities, such as beta-blockers and angiotensin-converting enzyme inhibitors, improve survival. Whether antithrombotic treatment is effective remains to be elucidated, although observations suggest a prothrombotic state in heart failure. This article focuses on this prothrombotic state and discusses the risk of thromboembolic events, pathophysiological mechanisms, and the potential role of anticoagulant treatment
AB - Systolic heart failure is a common syndrome whose Incidence is expected to increase. Several treatment modalities, such as beta-blockers and angiotensin-converting enzyme inhibitors, improve survival. Whether antithrombotic treatment is effective remains to be elucidated, although observations suggest a prothrombotic state in heart failure. This article focuses on this prothrombotic state and discusses the risk of thromboembolic events, pathophysiological mechanisms, and the potential role of anticoagulant treatment
U2 - https://doi.org/10.1055/s-0029-1234145
DO - https://doi.org/10.1055/s-0029-1234145
M3 - Article
C2 - 19739040
SN - 0094-6176
VL - 35
SP - 497
EP - 504
JO - Seminars in Thrombosis and Hemostasis
JF - Seminars in Thrombosis and Hemostasis
IS - 5
ER -