Targeting bacterial virulence: the coming out of type VII secretion inhibitors.

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Type VII (ESX) secretion systems of pathogenic mycobacteria, such as Mycobacterium tuberculosis, are crucial for intracellular survival, host cell lysis, and the subsequent cell-to-cell spread. In this issue of Cell Host & Microbe, Rybniker et al. (2014) have used these characteristics to identify two classes of type VII secretion inhibitors.
Original languageUndefined/Unknown
Pages (from-to)430-432
JournalCELL Host & Microbe
Issue number4
Publication statusPublished - 2014

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