The chicken CCAAT/enhancer binding protein alpha gene. Cloning, characterisation and tissue distribution

C. F. Calkhoven; S. I. Gringhuis; G. AB

doi:https://doi.org/10.1016/S0378-1119(97)00230-8

The chicken CCAAT/enhancer binding protein alpha gene. Cloning, characterisation and tissue distribution

C. F. Calkhoven, S. I. Gringhuis, G. AB

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Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Scopus)

Abstract

We present the cloning and sequencing of the gene encoding the chicken CCAAT/Enhancer Binding Protein alpha (cC/EBP alpha). The coding region and 1.5 kb of 5' flanking DNA from a CpG island. Comparison of the chicken C/EBP alpha sequence to the homologous proteins of other species reveals several evolutionary conserved regions. cC/EBP alpha mRNA expression is restricted to a subset of tissues with high expression in liver, lung and small intestine. Recombinant cC/EBP alpha binds to its cognate C/EBP binding site as a homodimer or as a heterodimer with the related cC/EBP beta/NF-M

Original language	English
Pages (from-to)	219-229
Journal	Gene
Volume	196
Issue number	1-2
DOIs	https://doi.org/10.1016/S0378-1119(97)00230-8
Publication status	Published - 1997

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https://doi.org/10.1016/S0378-1119(97)00230-8

Cite this

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title = "The chicken CCAAT/enhancer binding protein alpha gene. Cloning, characterisation and tissue distribution",

abstract = "We present the cloning and sequencing of the gene encoding the chicken CCAAT/Enhancer Binding Protein alpha (cC/EBP alpha). The coding region and 1.5 kb of 5' flanking DNA from a CpG island. Comparison of the chicken C/EBP alpha sequence to the homologous proteins of other species reveals several evolutionary conserved regions. cC/EBP alpha mRNA expression is restricted to a subset of tissues with high expression in liver, lung and small intestine. Recombinant cC/EBP alpha binds to its cognate C/EBP binding site as a homodimer or as a heterodimer with the related cC/EBP beta/NF-M",

author = "Calkhoven, {C. F.} and Gringhuis, {S. I.} and G. AB",

year = "1997",

doi = "https://doi.org/10.1016/S0378-1119(97)00230-8",

language = "English",

volume = "196",

pages = "219--229",

journal = "Gene",

issn = "0378-1119",

publisher = "Elsevier",

number = "1-2",

}

TY - JOUR

T1 - The chicken CCAAT/enhancer binding protein alpha gene. Cloning, characterisation and tissue distribution

AU - Calkhoven, C. F.

AU - Gringhuis, S. I.

AU - AB, G.

PY - 1997

Y1 - 1997

N2 - We present the cloning and sequencing of the gene encoding the chicken CCAAT/Enhancer Binding Protein alpha (cC/EBP alpha). The coding region and 1.5 kb of 5' flanking DNA from a CpG island. Comparison of the chicken C/EBP alpha sequence to the homologous proteins of other species reveals several evolutionary conserved regions. cC/EBP alpha mRNA expression is restricted to a subset of tissues with high expression in liver, lung and small intestine. Recombinant cC/EBP alpha binds to its cognate C/EBP binding site as a homodimer or as a heterodimer with the related cC/EBP beta/NF-M

AB - We present the cloning and sequencing of the gene encoding the chicken CCAAT/Enhancer Binding Protein alpha (cC/EBP alpha). The coding region and 1.5 kb of 5' flanking DNA from a CpG island. Comparison of the chicken C/EBP alpha sequence to the homologous proteins of other species reveals several evolutionary conserved regions. cC/EBP alpha mRNA expression is restricted to a subset of tissues with high expression in liver, lung and small intestine. Recombinant cC/EBP alpha binds to its cognate C/EBP binding site as a homodimer or as a heterodimer with the related cC/EBP beta/NF-M

U2 - https://doi.org/10.1016/S0378-1119(97)00230-8

DO - https://doi.org/10.1016/S0378-1119(97)00230-8

M3 - Article

C2 - 9322761

SN - 0378-1119

VL - 196

SP - 219

EP - 229

JO - Gene

JF - Gene

IS - 1-2

ER -