The co-occurrence of autistic and ADHD dimensions in adults: an etiological study in 17,770 twins.

T.J.C. Polderman, R.A. Hoekstra, D. Posthuma, H. Larsson

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Autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) often occur together. To obtain more insight in potential causes for the co-occurrence, this study examined the genetic and environmental etiology of the association between specific ASD and ADHD disorder dimensions. Self-reported data on ASD dimensions social and communication difficulties (ASDsc), and repetitive and restricted behavior and interests (ASDr), and ADHD dimensions inattention (IA), and hyperactivity/impulsivity (HI) were assessed in a community sample of 17 770 adult Swedish twins. Phenotypic, genetic and environmental associations between disorder dimensions were examined in a multivariate model, accounting for sex differences. ASDr showed the strongest associations with IA and HI in both sexes (r
Original languageEnglish
Article numbere435
JournalTranslational Psychiatry
Publication statusPublished - 2014

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