TY - JOUR
T1 - The co-occurrence of autistic and ADHD dimensions in adults: an etiological study in 17,770 twins.
AU - Polderman, T.J.C.
AU - Hoekstra, R.A.
AU - Posthuma, D.
AU - Larsson, H.
PY - 2014
Y1 - 2014
N2 - Autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) often occur together. To obtain more insight in potential causes for the co-occurrence, this study examined the genetic and environmental etiology of the association between specific ASD and ADHD disorder dimensions. Self-reported data on ASD dimensions social and communication difficulties (ASDsc), and repetitive and restricted behavior and interests (ASDr), and ADHD dimensions inattention (IA), and hyperactivity/impulsivity (HI) were assessed in a community sample of 17 770 adult Swedish twins. Phenotypic, genetic and environmental associations between disorder dimensions were examined in a multivariate model, accounting for sex differences. ASDr showed the strongest associations with IA and HI in both sexes (r
AB - Autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) often occur together. To obtain more insight in potential causes for the co-occurrence, this study examined the genetic and environmental etiology of the association between specific ASD and ADHD disorder dimensions. Self-reported data on ASD dimensions social and communication difficulties (ASDsc), and repetitive and restricted behavior and interests (ASDr), and ADHD dimensions inattention (IA), and hyperactivity/impulsivity (HI) were assessed in a community sample of 17 770 adult Swedish twins. Phenotypic, genetic and environmental associations between disorder dimensions were examined in a multivariate model, accounting for sex differences. ASDr showed the strongest associations with IA and HI in both sexes (r
U2 - https://doi.org/10.1038/tp.2014.84
DO - https://doi.org/10.1038/tp.2014.84
M3 - Article
C2 - 25180574
SN - 2158-3188
VL - 4
JO - Translational Psychiatry
JF - Translational Psychiatry
M1 - e435
ER -