The development of the CAT-EyeQ to measure vision-related quality of life in patients with exudative retinal diseases

Trijntje Petra Rausch-Koster

doi:https://doi.org/10.5463/thesis.377

The development of the CAT-EyeQ to measure vision-related quality of life in patients with exudative retinal diseases

Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

Abstract

This thesis focuses on the development of an instrument to measure the impact of exudative retina diseases on patients’ daily life. The development process was carried out in several stages: 1. Translating the Impact of Vision Impairment Profile (IVI) and subsequently assessing the content validity of the Dutch translated version of the IVI. The comprehensibility, comprehensiveness and relevance of the Dutch-IVI was assessed in this stage. 2. Supplementing the Dutch IVI with items measuring vision-related quality of life (based on several existing vision-related quality of life questionnaires) to broaden the item collection (item bank) and calibrating the item bank, called the EyeQ, in a cross-sectional study using a Graded Response Model (GRM) based on Item Response Theory (IRT) analyses. 3. Conducting computer adaptive test (CAT) simulations of the EyeQ to investigate what administration rules (stopping rules) should be set to optimize the performance of the CAT-EyeQ in clinical practice. 4. Investigating the usability of the CAT-EyeQ and identifying success factors and barriers for implementing the CAT-EyeQ in clinical practice. The CAT-EyeQ is a ‘low burden’ instrument measuring vision-related quality of life in an efficient way in ophthalmic clinical practice in patients with exudative retinal diseases. Future research is needed to confirm some of the psychometric properties of the CAT-EyeQ.

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution
Supervisors/Advisors	van Rens, G.H.M.B., Supervisor, External person van Nispen, Ruth Marie Antoinette, Co-supervisor, External person Verbraak, Franciscus, Co-supervisor van Rens, Ger, Supervisor van Nispen, Ruth, Co-supervisor
Award date	15 Nov 2023
DOIs	https://doi.org/10.5463/thesis.377
Publication status	Published - 15 Nov 2023

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https://doi.org/10.5463/thesis.377Licence: CC BY-ND

Cite this

@phdthesis{253e6566bdce404d8e1364a5761a60ec,

title = "The development of the CAT-EyeQ to measure vision-related quality of life in patients with exudative retinal diseases",

abstract = "This thesis focuses on the development of an instrument to measure the impact of exudative retina diseases on patients{\textquoteright} daily life. The development process was carried out in several stages: 1. Translating the Impact of Vision Impairment Profile (IVI) and subsequently assessing the content validity of the Dutch translated version of the IVI. The comprehensibility, comprehensiveness and relevance of the Dutch-IVI was assessed in this stage. 2. Supplementing the Dutch IVI with items measuring vision-related quality of life (based on several existing vision-related quality of life questionnaires) to broaden the item collection (item bank) and calibrating the item bank, called the EyeQ, in a cross-sectional study using a Graded Response Model (GRM) based on Item Response Theory (IRT) analyses. 3. Conducting computer adaptive test (CAT) simulations of the EyeQ to investigate what administration rules (stopping rules) should be set to optimize the performance of the CAT-EyeQ in clinical practice. 4. Investigating the usability of the CAT-EyeQ and identifying success factors and barriers for implementing the CAT-EyeQ in clinical practice. The CAT-EyeQ is a {\textquoteleft}low burden{\textquoteright} instrument measuring vision-related quality of life in an efficient way in ophthalmic clinical practice in patients with exudative retinal diseases. Future research is needed to confirm some of the psychometric properties of the CAT-EyeQ.",

author = "Rausch-Koster, {Trijntje Petra}",

year = "2023",

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doi = "https://doi.org/10.5463/thesis.377",

language = "English",

type = "Phd-Thesis - Research and graduation internal",

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N2 - This thesis focuses on the development of an instrument to measure the impact of exudative retina diseases on patients’ daily life. The development process was carried out in several stages: 1. Translating the Impact of Vision Impairment Profile (IVI) and subsequently assessing the content validity of the Dutch translated version of the IVI. The comprehensibility, comprehensiveness and relevance of the Dutch-IVI was assessed in this stage. 2. Supplementing the Dutch IVI with items measuring vision-related quality of life (based on several existing vision-related quality of life questionnaires) to broaden the item collection (item bank) and calibrating the item bank, called the EyeQ, in a cross-sectional study using a Graded Response Model (GRM) based on Item Response Theory (IRT) analyses. 3. Conducting computer adaptive test (CAT) simulations of the EyeQ to investigate what administration rules (stopping rules) should be set to optimize the performance of the CAT-EyeQ in clinical practice. 4. Investigating the usability of the CAT-EyeQ and identifying success factors and barriers for implementing the CAT-EyeQ in clinical practice. The CAT-EyeQ is a ‘low burden’ instrument measuring vision-related quality of life in an efficient way in ophthalmic clinical practice in patients with exudative retinal diseases. Future research is needed to confirm some of the psychometric properties of the CAT-EyeQ.

AB - This thesis focuses on the development of an instrument to measure the impact of exudative retina diseases on patients’ daily life. The development process was carried out in several stages: 1. Translating the Impact of Vision Impairment Profile (IVI) and subsequently assessing the content validity of the Dutch translated version of the IVI. The comprehensibility, comprehensiveness and relevance of the Dutch-IVI was assessed in this stage. 2. Supplementing the Dutch IVI with items measuring vision-related quality of life (based on several existing vision-related quality of life questionnaires) to broaden the item collection (item bank) and calibrating the item bank, called the EyeQ, in a cross-sectional study using a Graded Response Model (GRM) based on Item Response Theory (IRT) analyses. 3. Conducting computer adaptive test (CAT) simulations of the EyeQ to investigate what administration rules (stopping rules) should be set to optimize the performance of the CAT-EyeQ in clinical practice. 4. Investigating the usability of the CAT-EyeQ and identifying success factors and barriers for implementing the CAT-EyeQ in clinical practice. The CAT-EyeQ is a ‘low burden’ instrument measuring vision-related quality of life in an efficient way in ophthalmic clinical practice in patients with exudative retinal diseases. Future research is needed to confirm some of the psychometric properties of the CAT-EyeQ.

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