TY - JOUR
T1 - The diagnostic problem of endometrial stromal sarcoma: report on six cases
AU - Amant, Frédéric
AU - Moerman, Philippe
AU - Cadron, Isabelle
AU - Neven, Patrick
AU - Berteloot, Patrick
AU - Vergote, Ignace
PY - 2003
Y1 - 2003
N2 - The objective was to look for the incidence and clinicopathologic findings of women in whom the diagnosis of endometrial stromal sarcoma was initially missed. We carried out a retrospective analysis of cases treated at our institution from 1990 to 2002. In 6/15 (40%) women suffering from endometrial stromal sarcoma, the diagnosis initially was missed. The first diagnosis was uterine leiomyoma (n = 2), myxoid leiomyoma (n = 2), cellular leiomyoma (n = 1), or lymphatic disorder (n = 1). The final diagnosis was only made after consultation of a pathologist with a special interest in gynecological oncology. The mean age of this group was only 34 years (range, 18-53). A mean delay in diagnosis of 143 months (range, 24-408) resulted in stage 4 disease in 5/6 women. After a mean follow-up of 16 years (range, 5-43), 4/6 are without macroscopic evidence of disease, 1/6 with evidence of disease, and 1/6 died of disease. Especially in younger women, the diagnosis of endometrial stromal sarcoma can be problematic
AB - The objective was to look for the incidence and clinicopathologic findings of women in whom the diagnosis of endometrial stromal sarcoma was initially missed. We carried out a retrospective analysis of cases treated at our institution from 1990 to 2002. In 6/15 (40%) women suffering from endometrial stromal sarcoma, the diagnosis initially was missed. The first diagnosis was uterine leiomyoma (n = 2), myxoid leiomyoma (n = 2), cellular leiomyoma (n = 1), or lymphatic disorder (n = 1). The final diagnosis was only made after consultation of a pathologist with a special interest in gynecological oncology. The mean age of this group was only 34 years (range, 18-53). A mean delay in diagnosis of 143 months (range, 24-408) resulted in stage 4 disease in 5/6 women. After a mean follow-up of 16 years (range, 5-43), 4/6 are without macroscopic evidence of disease, 1/6 with evidence of disease, and 1/6 died of disease. Especially in younger women, the diagnosis of endometrial stromal sarcoma can be problematic
U2 - https://doi.org/10.1016/S0090-8258(03)00207-5
DO - https://doi.org/10.1016/S0090-8258(03)00207-5
M3 - Article
C2 - 12821339
SN - 0090-8258
VL - 90
SP - 37
EP - 43
JO - Gynecologic Oncology
JF - Gynecologic Oncology
IS - 1
ER -