The efficacy of Xialine ¿ in patients with xerostomia resulting from radiotherapy for head and neck cancer: a pilot study: A pilot-study

A.P. Jellema, H. Langendijk, L. Bergehenegouwen, W.A. van der Reijden, R. Leemans, L.E. Smeele, B.J. Slotman, L. Bergenhenegouwen

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Abstract

Changes in subjective sensations due to xerostomia before and after administration of Xialine, a xanthan gum-based saliva substitute, were evaluated in 30 patients with radiation-induced xerostomia using the QLQ-H&N35. Xerostomia in general decreased with both Xialine and placebo to almost the same degree. A trend was seen for Xialine to improve problems with speech and senses
Original languageUndefined/Unknown
Pages (from-to)157-160
Number of pages4
JournalRadiotherapy and oncology
Volume59
Issue number2
DOIs
Publication statusPublished - 1 May 2001

Keywords

  • Head and neck cancer
  • Irradiation
  • Quality of life
  • Saliva substitute
  • Xerostomia

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