Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 115-208 |
| Journal | Haematologica |
| Volume | 101 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 2016 |
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In: Haematologica, Vol. 101, No. 2, 02.2016, p. 115-208.
Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - The European Hematology Association Roadmap for European Hematology Research: a consensus document
AU - Engert, Andreas
AU - Balduini, Carlo
AU - Brand, Anneke
AU - Coiffier, Bertrand
AU - Cordonnier, Catherine
AU - Döhner, Hartmut
AU - de Wit, Thom Duyvené
AU - Eichinger, Sabine
AU - Fibbe, Willem
AU - Green, Tony
AU - de Haas, Fleur
AU - Iolascon, Achille
AU - Jaffredo, Thierry
AU - Rodeghiero, Francesco
AU - Salles, Gilles
AU - Schuringa, Jan Jacob
AU - AUTHOR GROUP
AU - André, Marc
AU - Andre-Schmutz, Isabelle
AU - Bacigalupo, Andrea
AU - Bochud, Pierre-Yves
AU - Boer, Monique den
AU - Bonini, Chiara
AU - Camaschella, Clara
AU - Cant, Andrew
AU - Cappellini, Maria Domenica
AU - Cazzola, Mario
AU - Celso, Cristina Lo
AU - Dimopoulos, Meletios
AU - Douay, Luc
AU - Dzierzak, Elaine
AU - Einsele, Hermann
AU - Ferreri, Andrés
AU - de Franceschi, Lucia
AU - Gaulard, Philippe
AU - Gottgens, Berthold
AU - Greinacher, Andreas
AU - Gresele, Paolo
AU - Gribben, John
AU - de Haan, Gerald
AU - Hansen, John-Bjarne
AU - Hochhaus, Andreas
AU - Kadir, Rezan
AU - Kaveri, Srini
AU - Kouskoff, Valerie
AU - Kühne, Thomas
AU - Kyrle, Paul
AU - Ljungman, Per
AU - Reitsma, Pieter
AU - Zaaijer, Hans
AU - Zeerleder, Sacha
AU - Kuehne, Thomas
AU - Maschmeyer, Georg
AU - Mendez-Ferrer, Simon
AU - Milsom, Michael
AU - Mummery, Christine
AU - Ossenkoppele, Gert
AU - Pecci, Alessandro
AU - Peyvandi, Flora
AU - Philipsen, Sjaak
AU - Maria Ribera, Jose
AU - Risitano, Antonio
AU - Rivella, Stefano
AU - Ruf, Wolfram
AU - Schroeder, Timm
AU - Scully, Marie
AU - Socie, Gerard
AU - Staal, Frank
AU - Stanworth, Simon
AU - Stauder, Reinhard
AU - Stilgenbauer, Stephan
AU - Tamary, Hannah
AU - Theilgaard-Monch, Kim
AU - Thein, Swee Lay
AU - Tilly, Herve
AU - Trneny, Marek
AU - Vainchenker, William
AU - Vannucchi, Alessandro Maria
AU - Viscoli, Claudio
AU - Vrielink, Hans
AU - Zanella, Alberto
AU - Zolla, Lello
AU - Zwaginga, Jaap Jan
AU - Martinez, Patricia Aguilar
AU - van den Akker, Emile
AU - Allard, Shubha
AU - Anagnou, Nicholas
AU - Anagnou, Nicholas
AU - Andrau, Jean-Christophe
AU - Angelucci, Emanuele
AU - Anstee, David
AU - Aurer, Igor
AU - Avet-Loiseau, Herve
AU - Aydinok, Yesim
AU - Bakchoul, Tamam
AU - Balduini, Alessandra
AU - Barcellini, Wilma
AU - Baruch, Dominique
AU - Baruchel, Andre
AU - Bayry, Jagadeesh
AU - Bento, Celeste
AU - van den Berg, Anke
AU - Bernardi, Rosa
AU - Bianchi, Paola
AU - Bigas, Anna
AU - Biondi, Andrea
AU - Bohonek, Milos
AU - Bonnet, Dominique
AU - Borchmann, Peter
AU - Borregaard, Niels
AU - Braekkan, Sigrid
AU - van den Brink, Marcel
AU - Brodin, Ellen
AU - Bullinger, Lars
AU - Buske, Christian
AU - Butzeck, Barbara
AU - Cammenga, Jorg
AU - Campo, Elias
AU - Carbone, Antonino
AU - Cervantes, Francisco
AU - Cesaro, Simone
AU - Charbord, Pierre
AU - Claas, Frans
AU - Cohen, Hannah
AU - Conard, Jacqueline
AU - Coppo, Paul
AU - Vives Corrons, Joan-Lluis
AU - da Costa, Lydie
AU - Davi, Frederic
AU - Delwel, Ruud
AU - Dianzani, Irma
AU - Domanovic, Dragoslav
AU - Donnelly, Peter
AU - Drnovsek, Tadeja Dov
AU - Dreyling, Martin
AU - Du, Ming-Qing
AU - Du, Ming-Qing
AU - Durand, Charles
AU - Efremov, Dimitar
AU - Eleftheriou, Androulla
AU - Elion, Jacques
AU - Emonts, Marieke
AU - Engelhardt, Monika
AU - Ezine, Sophie
AU - Falkenburg, Fred
AU - Favier, Remi
AU - Federico, Massimo
AU - Fenaux, Pierre
AU - Fitzgibbon, Jude
AU - Flygare, Johan
AU - Foa, Robin
AU - Forrester, Lesley
AU - Galacteros, Frederic
AU - Garagiola, Isabella
AU - Gardiner, Chris
AU - Garraud, Olivier
AU - van Geet, Christel
AU - Geiger, Hartmut
AU - Geissler, Jan
AU - Germing, Ulrich
AU - Ghevaert, Cedric
AU - Girelli, Domenico
AU - Godeau, Bertrand
AU - Goekbuget, Nicola
AU - Goldschmidt, Hartmut
AU - Goodeve, Anne
AU - Graf, Thomas
AU - Graziadei, Giovanna
AU - Griesshammer, Martin
AU - Gruel, Yves
AU - Guilhot, Francois
AU - von Gunten, Stephan
AU - Gyssens, Inge
AU - Halter, Jorg
AU - Harrison, Claire
AU - Harteveld, Cornelis
AU - Hellstrom-Lindberg, Eva
AU - Hermine, Olivier
AU - Higgs, Douglas
AU - Hillmen, Peter
AU - Hirsch, Hans
AU - Hoskin, Peter
AU - Huls, Gerwin
AU - Inati, Adlette
AU - Johnson, Peter
AU - Kattamis, Antonis
AU - Kiefel, Volker
AU - Kleanthous, Marina
AU - Klump, Hannes
AU - Krause, Daniela
AU - Hovinga, Johanna Kremer
AU - Lacaud, Georges
AU - Lacroix-Desmazes, Sebastien
AU - Landman-Parker, Judith
AU - LeGouill, Steven
AU - Lenz, Georg
AU - von Lilienfeld-Toal, Marie
AU - von Lindern, Marieke
AU - Lopez-Guillermo, Armando
AU - Lopriore, Enrico
AU - Lozano, Miguel
AU - MacIntyre, Elizabeth
AU - Makris, Michael
AU - Mannhalter, Christine
AU - Martens, Joost
AU - Mathas, Stephan
AU - Matzdorff, Axel
AU - Medvinsky, Alexander
AU - Menendez, Pablo
AU - Migliaccio, Anna Rita
AU - Miharada, Kenichi
AU - Mikulska, Malgorzata
AU - Minard, Veronique
AU - Montalban, Carlos
AU - de Montalembert, Mariane
AU - Montserrat, Emili
AU - Morange, Pierre-Emmanuel
AU - Mountford, Joanne
AU - Muckenthaler, Martina
AU - Mueller-Tidow, Carsten
AU - Mumford, Andrew
AU - Nadel, Bertrand
AU - Navarro, Jose-Tomas
AU - el Nemer, Wassim
AU - Noizat-Pirenne, France
AU - O'Mahony, Brian
AU - Oldenburg, Johannes
AU - Olsson, Martin
AU - Oostendorp, Robert
AU - Palumbo, Antonio
AU - Passamonti, Francesco
AU - Patient, Roger
AU - de Latour, Regis Peffault
AU - Pflumio, Francoise
AU - Pierelli, Luca
AU - Piga, Antonio
AU - Pollard, Debra
AU - Raaijmakers, Marc
AU - Radford, John
AU - Rambach, Ralf
AU - Rao, A. Koneti
AU - Raslova, Hana
AU - Rebulla, Paolo
AU - Rees, David
AU - Ribrag, Vincent
AU - Rijneveld, Anita
AU - Rinalducci, Sara
AU - Robak, Tadeusz
AU - Roberts, Irene
AU - Rodrigues, Charlene
AU - Rosendaal, Frits
AU - Rosenwald, Andreas
AU - Rule, Simon
AU - Russo, Roberta
AU - Saglio, Guiseppe
AU - Sanchez, Mayka
AU - Scharf, Ruediger E.
AU - Schlenke, Peter
AU - Semple, John
AU - Sierra, Jorge
AU - So-Osman, Cynthia
AU - Manuel Soria, Jose
AU - Stamatopoulos, Kostas
AU - Stegmayr, Bernd
AU - Stunnenberg, Henk
AU - Swinkels, Dorine
AU - Taborda Barata, Joao Pedro
AU - Taghon, Tom
AU - Taher, Ali
AU - Terpos, Evangelos
AU - Thachil, Jecko
AU - Tissot, Jean Daniel
AU - Touw, Ivo
AU - Toye, Ash
AU - Trappe, Ralf
AU - Traverse-Glehen, Alexandra
AU - Unal, Sule
AU - Vaulont, Sophie
AU - Viprakasit, Vip
AU - Vitolo, Umberto
AU - van Wijk, Richard
AU - Wojtowicz, Agnieszka
AU - Zieger, Barbara
PY - 2016/2
Y1 - 2016/2
N2 - The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at €23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap.The EHA Roadmap identifies nine 'sections' in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders.The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients
AB - The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at €23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap.The EHA Roadmap identifies nine 'sections' in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders.The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients
U2 - https://doi.org/10.3324/haematol.2015.136739
DO - https://doi.org/10.3324/haematol.2015.136739
M3 - Article
C2 - 26819058
SN - 0390-6078
VL - 101
SP - 115
EP - 208
JO - Haematologica
JF - Haematologica
IS - 2
ER -