The Future of Childhood Cancer Survivorship: Challenges and Opportunities for Continued Progress

Stephanie B. Dixon; Eric J. Chow; Lars Hjorth; Melissa M. Hudson; Leontien C. M. Kremer; Lindsay M. Morton; Paul C. Nathan; Kirsten K. Ness; Kevin C. Oeffinger; Gregory T. Armstrong

doi:https://doi.org/10.1016/j.pcl.2020.07.013

The Future of Childhood Cancer Survivorship: Challenges and Opportunities for Continued Progress

Stephanie B. Dixon, Eric J. Chow, Lars Hjorth, Melissa M. Hudson, Leontien C. M. Kremer, Lindsay M. Morton, Paul C. Nathan, Kirsten K. Ness, Kevin C. Oeffinger, Gregory T. Armstrong

Research output: Contribution to journal › Review article › Academic › peer-review

17 Citations (Scopus)

Abstract

As treatment evolves and the population who survive childhood cancer ages and increases in number, researchers must use novel approaches to prevent, identify and mitigate adverse effects of treatment. Future priorities include collaborative efforts to pool large cohort data to improve detection of late effects, identify late effects of novel therapies, and determine the contribution of genetic factors along with physiologic and accelerated aging among survivors. This knowledge should translate to individual risk prediction and prevention strategies. Finally, we must utilize health services research and implementation science to improve adoption of survivorship care recommendations outside of specialized pediatric oncology centers.

Original language	English
Pages (from-to)	1237-1251
Number of pages	15
Journal	Pediatric clinics of North America
Volume	67
Issue number	6
DOIs	https://doi.org/10.1016/j.pcl.2020.07.013
Publication status	Published - 1 Dec 2020

Keywords

Adolescent
Cancer
Child
Delivery of health care
Neoplasms
Survivor
Treatment outcome

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https://doi.org/10.1016/j.pcl.2020.07.013

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title = "The Future of Childhood Cancer Survivorship: Challenges and Opportunities for Continued Progress",

abstract = "As treatment evolves and the population who survive childhood cancer ages and increases in number, researchers must use novel approaches to prevent, identify and mitigate adverse effects of treatment. Future priorities include collaborative efforts to pool large cohort data to improve detection of late effects, identify late effects of novel therapies, and determine the contribution of genetic factors along with physiologic and accelerated aging among survivors. This knowledge should translate to individual risk prediction and prevention strategies. Finally, we must utilize health services research and implementation science to improve adoption of survivorship care recommendations outside of specialized pediatric oncology centers.",

keywords = "Adolescent, Cancer, Child, Delivery of health care, Neoplasms, Survivor, Treatment outcome",

author = "Dixon, {Stephanie B.} and Chow, {Eric J.} and Lars Hjorth and Hudson, {Melissa M.} and Kremer, {Leontien C. M.} and Morton, {Lindsay M.} and Nathan, {Paul C.} and Ness, {Kirsten K.} and Oeffinger, {Kevin C.} and Armstrong, {Gregory T.}",

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AU - Dixon, Stephanie B.

AU - Chow, Eric J.

AU - Hjorth, Lars

AU - Hudson, Melissa M.

AU - Kremer, Leontien C. M.

AU - Morton, Lindsay M.

AU - Nathan, Paul C.

AU - Ness, Kirsten K.

AU - Oeffinger, Kevin C.

AU - Armstrong, Gregory T.

PY - 2020/12/1

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N2 - As treatment evolves and the population who survive childhood cancer ages and increases in number, researchers must use novel approaches to prevent, identify and mitigate adverse effects of treatment. Future priorities include collaborative efforts to pool large cohort data to improve detection of late effects, identify late effects of novel therapies, and determine the contribution of genetic factors along with physiologic and accelerated aging among survivors. This knowledge should translate to individual risk prediction and prevention strategies. Finally, we must utilize health services research and implementation science to improve adoption of survivorship care recommendations outside of specialized pediatric oncology centers.

AB - As treatment evolves and the population who survive childhood cancer ages and increases in number, researchers must use novel approaches to prevent, identify and mitigate adverse effects of treatment. Future priorities include collaborative efforts to pool large cohort data to improve detection of late effects, identify late effects of novel therapies, and determine the contribution of genetic factors along with physiologic and accelerated aging among survivors. This knowledge should translate to individual risk prediction and prevention strategies. Finally, we must utilize health services research and implementation science to improve adoption of survivorship care recommendations outside of specialized pediatric oncology centers.

KW - Adolescent

KW - Cancer

KW - Child

KW - Delivery of health care

KW - Neoplasms

KW - Survivor

KW - Treatment outcome

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JO - Pediatric clinics of North America

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IS - 6

ER -

The Future of Childhood Cancer Survivorship: Challenges and Opportunities for Continued Progress

Abstract

Keywords

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