TY - JOUR
T1 - The impact of being overweight or obese on 12 month clinical recovery in patients following lumbar microdiscectomy for radiculopathy
AU - Willems, Stijn J.
AU - Coppieters, Michel W.
AU - Rooker, Servan
AU - Orzali, Luca
AU - Kittelson, Andrew J.
AU - Ostelo, Raymond W.
AU - Kempen, Diederik H. R.
AU - Scholten-Peeters, Gwendolyne G. M.
N1 - Funding Information: During the preparation of this work, the author(s) used Grammarly to enhance grammar and improve reading flow. Following the use of this service, the author(s) meticulously reviewed and adjusted the content as necessary. The author(s) bear full responsibility for the final content of the publication. The authors would like to thank Kliniek ViaSana, Mill, The Netherlands for their cooperation in this study and in particular Klaartje Pijnappels and Yvette Pronk for their assistance with the data collection. Funds were received from the Innovation fund ViaSana. No relevant financial activities outside the submitted work. Author disclosures: SJW: Grant: ViaSana (C). MWC: Nothing to disclose. SR: Nothing to disclose. LO: Nothing to disclose. AJK: Nothing to disclose. RWO: Grants: DBRIC (D), Dutch-Belgian Research Institute of Chiropractic (F), ZonMw (F), RAAK MKB (F), ZonMw (G). DHRK: Nothing to disclose. GGMS-P: Grant: Innovation fund ViaSana (C). Publisher Copyright: © 2023 The Author(s)
PY - 2023/11
Y1 - 2023/11
N2 - BACKGROUND CONTEXT: The proportion of patients who undergo lumbar microdiscectomy due to lumbar radiculopathy who are also overweight or obese is high. However, whether high body mass index (BMI) affects clinical outcomes is not well-studied. PURPOSE: To investigate the difference in the clinical course between normal weight, overweight, and obese patients with radiculopathy who underwent lumbar microdiscectomy followed by physical therapy and to evaluate whether high BMI is associated with poor recovery. STUDY DESIGN/SETTING: A prospective cohort study with a 12-month follow-up was conducted in a multidisciplinary clinic. PATIENT SAMPLE: We included 583 patients (median (IQR) age: 45 (35–52) years; 41% female) with clinical signs and symptoms of lumbar radiculopathy, consistent with magnetic resonance imaging findings, who underwent microdiscectomy followed by postoperative physical therapy. OUTCOME MEASURES: Outcomes were leg pain and back pain intensity measured with a visual analogue scale, disability measured with the Roland Morris Disability Questionnaire at 3 and 12-month follow-ups, and complications. METHODS: Patients were classified as being normal weight (46.9%), overweight (38.4%), or obese (14.7%). A linear mixed-effects model was used to assess the difference in the clinical course of pain and disability between the three BMI categories. The association between BMI and outcomes was evaluated using univariable and multivariable logistic regression analyses. RESULTS: All three patient groups experienced a significant improvement in leg pain, back pain, and disability over 3 and 12-month follow-up. Patients who were overweight, obese, or normal weight experienced comparable leg pain (p=.14) and disability (p=.06) over the clinical course (p=.14); however, obese patients experienced higher back pain (MD=−6.81 [95%CI: −13.50 to −0.14]; p=.03). The difference in back pain scores was not clinically relevant. CONCLUSIONS: In the first year following lumbar microdiscectomy, patients demonstrated clinical improvements and complications that were unrelated to their preoperative BMI.
AB - BACKGROUND CONTEXT: The proportion of patients who undergo lumbar microdiscectomy due to lumbar radiculopathy who are also overweight or obese is high. However, whether high body mass index (BMI) affects clinical outcomes is not well-studied. PURPOSE: To investigate the difference in the clinical course between normal weight, overweight, and obese patients with radiculopathy who underwent lumbar microdiscectomy followed by physical therapy and to evaluate whether high BMI is associated with poor recovery. STUDY DESIGN/SETTING: A prospective cohort study with a 12-month follow-up was conducted in a multidisciplinary clinic. PATIENT SAMPLE: We included 583 patients (median (IQR) age: 45 (35–52) years; 41% female) with clinical signs and symptoms of lumbar radiculopathy, consistent with magnetic resonance imaging findings, who underwent microdiscectomy followed by postoperative physical therapy. OUTCOME MEASURES: Outcomes were leg pain and back pain intensity measured with a visual analogue scale, disability measured with the Roland Morris Disability Questionnaire at 3 and 12-month follow-ups, and complications. METHODS: Patients were classified as being normal weight (46.9%), overweight (38.4%), or obese (14.7%). A linear mixed-effects model was used to assess the difference in the clinical course of pain and disability between the three BMI categories. The association between BMI and outcomes was evaluated using univariable and multivariable logistic regression analyses. RESULTS: All three patient groups experienced a significant improvement in leg pain, back pain, and disability over 3 and 12-month follow-up. Patients who were overweight, obese, or normal weight experienced comparable leg pain (p=.14) and disability (p=.06) over the clinical course (p=.14); however, obese patients experienced higher back pain (MD=−6.81 [95%CI: −13.50 to −0.14]; p=.03). The difference in back pain scores was not clinically relevant. CONCLUSIONS: In the first year following lumbar microdiscectomy, patients demonstrated clinical improvements and complications that were unrelated to their preoperative BMI.
KW - Body mass index
KW - Disc herniation
KW - Lumbar surgery
KW - Obesity
KW - Prognosis
KW - Rehabilitation
KW - Sciatica
UR - http://www.scopus.com/inward/record.url?scp=85178648105&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/j.spinee.2023.10.023
DO - https://doi.org/10.1016/j.spinee.2023.10.023
M3 - Article
C2 - 37935285
SN - 1529-9430
VL - 24
SP - 625
EP - 633
JO - Spine Journal
JF - Spine Journal
IS - 4
ER -