The importance of fluence rate in photodynamic therapy: is there a parallel with ionizing radiation dose-rate effects?

Ruth B. Veenhuizen; F. A. Stewart

doi:https://doi.org/10.1016/0167-8140(95)01626-R

The importance of fluence rate in photodynamic therapy: is there a parallel with ionizing radiation dose-rate effects?

Ruth B. Veenhuizen, F. A. Stewart

Research output: Contribution to journal › Article › Academic › peer-review

51 Citations (Scopus)

Abstract

Several similarities can be found between dose-rate effects in radiotherapy and fluence-rate effects in photodynamic therapy (PDT). At low dose rates repair of sublethal damage can occur, whereas at high dose rates oxygen depletion can decrease the effects of both therapies. The available literature for fluence-rate effects in PDT is discussed here in relation to therapeutic implications.

Original language	English
Pages (from-to)	131-135
Number of pages	5
Journal	Radiotherapy and oncology
Volume	37
Issue number	2
DOIs	https://doi.org/10.1016/0167-8140(95)01626-R
Publication status	Published - Nov 1995

Keywords

Dose-rate effect
Fluence rate
Ionizing radiation
Photodynamic therapy

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https://doi.org/10.1016/0167-8140(95)01626-R

Cite this

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The importance of fluence rate in photodynamic therapy: is there a parallel with ionizing radiation dose-rate effects?

Abstract

Keywords

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