TY - JOUR
T1 - The Malone antegrade continence enema procedure: the Amsterdam experience
AU - Hoekstra, Lisette T.
AU - Kuijper, Caroline F.
AU - Bakx, Roel
AU - Heij, Hugo A.
AU - Aronson, Daniel C.
AU - Benninga, Marc A.
PY - 2011
Y1 - 2011
N2 - The Malone antegrade continence enema (MACE) procedure has been previously described as a safe and effective option for the treatment of children with chronic defecation disorders when maximal medical therapy and conventional treatment have failed. To evaluate clinical success, complications, and quality of life of children with chronic defecation disorders with a MACE stoma. A retrospective analysis of 23 patients who underwent the construction of a MACE stoma was performed. Preoperative and postoperative data were evaluated. A specific questionnaire was used to assess patient satisfaction. A significant increase was found in defecation frequency (1.0 [range, 0-4] pretreatment vs 5.5 [range, 0-28] posttreatment per week; P < .006) and a significant decrease in fecal incontinence frequency (10 [range, 0-14] pretreatment vs 0 [range, 0-14] posttreatment per week; P < .034). Postoperative complications of the MACE procedure were fecal leakage (43%), wound infection (52%), and stomal stenosis (39%). A total of 86% of the patients were satisfied with the results of the Malone stoma (n = 21). The MACE procedure is an effective treatment in children with intractable defecation disorders. Postoperative complications are, however, not uncommon. Further refinement of the technique focused to reduce the complication rate is necessary to expand the application of this approach
AB - The Malone antegrade continence enema (MACE) procedure has been previously described as a safe and effective option for the treatment of children with chronic defecation disorders when maximal medical therapy and conventional treatment have failed. To evaluate clinical success, complications, and quality of life of children with chronic defecation disorders with a MACE stoma. A retrospective analysis of 23 patients who underwent the construction of a MACE stoma was performed. Preoperative and postoperative data were evaluated. A specific questionnaire was used to assess patient satisfaction. A significant increase was found in defecation frequency (1.0 [range, 0-4] pretreatment vs 5.5 [range, 0-28] posttreatment per week; P < .006) and a significant decrease in fecal incontinence frequency (10 [range, 0-14] pretreatment vs 0 [range, 0-14] posttreatment per week; P < .034). Postoperative complications of the MACE procedure were fecal leakage (43%), wound infection (52%), and stomal stenosis (39%). A total of 86% of the patients were satisfied with the results of the Malone stoma (n = 21). The MACE procedure is an effective treatment in children with intractable defecation disorders. Postoperative complications are, however, not uncommon. Further refinement of the technique focused to reduce the complication rate is necessary to expand the application of this approach
U2 - https://doi.org/10.1016/j.jpedsurg.2011.04.050
DO - https://doi.org/10.1016/j.jpedsurg.2011.04.050
M3 - Article
C2 - 21843730
SN - 0022-3468
VL - 46
SP - 1603
EP - 1608
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
IS - 8
ER -