TY - JOUR
T1 - The Optimal Management of Acute Febrile Encephalopathy in the Aged Patient
T2 - A Systematic Review
AU - Sheybani, Fereshte
AU - Naderi, Hamid Reza
AU - Sajjadi, Sareh
N1 - Publisher Copyright: © 2016 Fereshte Sheybani et al.
PY - 2016
Y1 - 2016
N2 - The elderly comprise less than 13 percent of world population. Nonetheless, they represent nearly half of all hospitalized adults. Acute change in mental status from baseline is commonly seen among the elderly even when the main process does not involve the central nervous system. The term "geriatric syndrome" is used to capture those clinical conditions in older people that do not fit into discrete disease categories, including delirium, falls, frailty, dizziness, syncope, and urinary incontinence. Despite the growing number of elderly population, especially those who require hospitalization and the high burden of common infections accompanied by encephalopathy among them, there are several unresolved questions regarding the optimal management they deserve. The questions posed in this systematic review concern the need to rule out CNS infection in all elderly patients presented with fever and altered mental status in the routine management of febrile encephalopathy. In doing so, we sought to identify all potentially relevant articles using searches of web-based databases with no language restriction. Finally, we reviewed 93 research articles that were relevant to each part of our study. No prospective study was found to address how should AFE in the aged be optimally managed.
AB - The elderly comprise less than 13 percent of world population. Nonetheless, they represent nearly half of all hospitalized adults. Acute change in mental status from baseline is commonly seen among the elderly even when the main process does not involve the central nervous system. The term "geriatric syndrome" is used to capture those clinical conditions in older people that do not fit into discrete disease categories, including delirium, falls, frailty, dizziness, syncope, and urinary incontinence. Despite the growing number of elderly population, especially those who require hospitalization and the high burden of common infections accompanied by encephalopathy among them, there are several unresolved questions regarding the optimal management they deserve. The questions posed in this systematic review concern the need to rule out CNS infection in all elderly patients presented with fever and altered mental status in the routine management of febrile encephalopathy. In doing so, we sought to identify all potentially relevant articles using searches of web-based databases with no language restriction. Finally, we reviewed 93 research articles that were relevant to each part of our study. No prospective study was found to address how should AFE in the aged be optimally managed.
UR - http://www.scopus.com/inward/record.url?scp=84959315702&partnerID=8YFLogxK
U2 - https://doi.org/10.1155/2016/5273651
DO - https://doi.org/10.1155/2016/5273651
M3 - Review article
SN - 1687-708X
VL - 2016
JO - Interdisciplinary perspectives on infectious diseases
JF - Interdisciplinary perspectives on infectious diseases
M1 - 5273651
ER -