TY - JOUR
T1 - The Power of Flash Mob Research
T2 - Conducting a Nationwide Observational Clinical Study on Capillary Refill Time in a Single Day
AU - FAMOUS Study Group
AU - Alsma, Jelmer
AU - van Saase, Jan L.C.M.
AU - Nanayakkara, Prabath W.B.
AU - Schouten, W. E.M.Ineke
AU - Baten, Anique
AU - Bauer, Martijn P.
AU - Holleman, Frits
AU - Ligtenberg, Jack J.M.
AU - Stassen, Patricia M.
AU - Kaasjager, Karin H.A.H.
AU - Haak, Harm R.
AU - Bosch, Frank H.
AU - Schuit, Stephanie C.E.
AU - Arends, Joris J.
AU - Buunk, Gerba
AU - Veldman, Bart J.A.
AU - Ammerlaan, Heidi S.M.
AU - Sankatsing, Sanjay U.C.
AU - Jacobs, Esther M.G.
AU - van Bemmel, Thomas
AU - Ruiter, Rikje
AU - Bots, Eva M.T.
AU - Reuters, Ralf A.
AU - Carels, Ginette
AU - Diepeveen, Sabine H.A.
AU - Heitz, Anne Floor N.
AU - Hien van Leeuwen-Nguyen, T. T.
AU - Keurlings, Pim A.J.
AU - Barnhard, Renske
AU - Schreurs, Rachel H.P.
AU - ter Avest, Ewoud
AU - Brink, Hans S.
AU - van Kinschot, Caroline M.J.
AU - van der Hoeven, Niels
AU - van der Zijden, Mark A.
AU - Hageman, Ilse M.G.
AU - Roeleveld, Timo C.
AU - Klomp, Carolijn M.C.
AU - Dekker, Douwe
AU - Blom, Anneke
AU - Wesselius, Hilde M.
AU - van Bemmel, Marieke M.
AU - de Jong, Ben
AU - Hillen, Judith
AU - Langbroek, Ginger Beau
AU - de Bie, Sandra
AU - AUTHOR GROUP
PY - 2017/5/1
Y1 - 2017/5/1
N2 - Background Capillary refill time (CRT) is a clinical test used to evaluate the circulatory status of patients; various methods are available to assess CRT. Conventional clinical research often demands large numbers of patients, making it costly, labor-intensive, and time-consuming. We studied the interobserver agreement on CRT in a nationwide study by using a novel method of research called flash mob research (FMR). Methods Physicians in the Netherlands were recruited by using word-of-mouth referrals, conventional media, and social media to participate in a nationwide, single-day, “nine-to-five,” multicenter, cross-sectional, observational study to evaluate CRT. Patients aged ≥ 18 years presenting to the ED or who were hospitalized were eligible for inclusion. CRT was measured independently (by two investigators) at the patient's sternum and distal phalanx after application of pressure for 5 s (5s) and 15 s (15s). Results On October 29, 2014, a total of 458 investigators in 38 Dutch hospitals enrolled 1,734 patients. The mean CRT measured at the distal phalanx were 2.3 s (5s, SD 1.1) and 2.4 s (15s, SD 1.3). The mean CRT measured at the sternum was 2.6 s (5s, SD 1.1) and 2.7 s (15s, SD 1.1). Interobserver agreement was higher for the distal phalanx (κ value, 0.40) than for the sternum (κ value, 0.30). Conclusions Interobserver agreement on CRT is, at best, moderate. CRT measured at the distal phalanx yielded higher interobserver agreement compared with sternal CRT measurements. FMR proved a valuable instrument to investigate a relatively simple clinical question in an inexpensive, quick, and reliable manner.
AB - Background Capillary refill time (CRT) is a clinical test used to evaluate the circulatory status of patients; various methods are available to assess CRT. Conventional clinical research often demands large numbers of patients, making it costly, labor-intensive, and time-consuming. We studied the interobserver agreement on CRT in a nationwide study by using a novel method of research called flash mob research (FMR). Methods Physicians in the Netherlands were recruited by using word-of-mouth referrals, conventional media, and social media to participate in a nationwide, single-day, “nine-to-five,” multicenter, cross-sectional, observational study to evaluate CRT. Patients aged ≥ 18 years presenting to the ED or who were hospitalized were eligible for inclusion. CRT was measured independently (by two investigators) at the patient's sternum and distal phalanx after application of pressure for 5 s (5s) and 15 s (15s). Results On October 29, 2014, a total of 458 investigators in 38 Dutch hospitals enrolled 1,734 patients. The mean CRT measured at the distal phalanx were 2.3 s (5s, SD 1.1) and 2.4 s (15s, SD 1.3). The mean CRT measured at the sternum was 2.6 s (5s, SD 1.1) and 2.7 s (15s, SD 1.1). Interobserver agreement was higher for the distal phalanx (κ value, 0.40) than for the sternum (κ value, 0.30). Conclusions Interobserver agreement on CRT is, at best, moderate. CRT measured at the distal phalanx yielded higher interobserver agreement compared with sternal CRT measurements. FMR proved a valuable instrument to investigate a relatively simple clinical question in an inexpensive, quick, and reliable manner.
KW - biomedical research
KW - capillary refill time
KW - data collection
KW - physiology
UR - http://www.scopus.com/inward/record.url?scp=85019096958&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/j.chest.2016.11.035
DO - https://doi.org/10.1016/j.chest.2016.11.035
M3 - Article
C2 - 27940191
SN - 0012-3692
VL - 151
SP - 1106
EP - 1113
JO - Chest
JF - Chest
IS - 5
ER -