The renin-angiotensin system and vascular function. The role of angiotensin II, angiotensin-converting enzyme, and alternative conversion of angiotensin I

A. Roks, H. Buikema, Y. M. Pinto, W. H. van Gilst

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19 Citations (Scopus)

Abstract

The renin-angiotensin system has been implicated in vascular function and disease. Angiotensin-converting enzyme and angiotensin II are believed to be the most important components. However, alternative factors, such as angiotensin-I/II-(1-7) and chymase, have also been shown to be of significance in animal models. In this paper, we review some facts and provide additional proof for the functional significance of angiotensin-I/II-(1-7) and chymase in humans
Original languageEnglish
Pages (from-to)119-124
JournalHeart and vessels
Volume12
Issue numberSuppl. 12
Publication statusPublished - 1997

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