Abstract
Although light skin types are associated with increased skin cancer risk, a lower incidence of both melanoma and nonmelanoma skin cancer (NMSC) has been reported in patients with vitiligo. We performed a systematic review and meta-analysis on the NMSC risk in patients with vitiligo, indicating a reduced relative risk ratio of NMSC in vitiligo. Furthermore, we propose a series of hypotheses on the underlying mechanisms, including both immune-mediated and nonimmune-mediated pathways. This study reveals insights into the relationship between vitiligo and keratinocyte cancer and can also be used to better inform patients with vitiligo.
Original language | English |
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Pages (from-to) | 234-242 |
Number of pages | 9 |
Journal | Journal of Investigative Dermatology |
Volume | 144 |
Issue number | 2 |
Early online date | 2 Oct 2023 |
DOIs | |
Publication status | Published - Feb 2024 |