The toll-like receptor 4 (TLR4) Asp299Gly polymorphism is associated with colonic localisation of Crohn's disease without a major role for the Saccharomyces cerevisiae mannan-LBP-CD14-TLR4 pathway

S Ouburg, R Mallant-Hent, J B A Crusius, A A van Bodegraven, C J J Mulder, R Linskens, A S Peña, S A Morré

Research output: Contribution to journalArticleAcademicpeer-review

51 Citations (Scopus)
Original languageEnglish
Pages (from-to)439-40
Number of pages2
Issue number3
Publication statusPublished - Mar 2005


  • Crohn Disease/genetics
  • Genetic Predisposition to Disease
  • Humans
  • Membrane Glycoproteins/genetics
  • Polymorphism, Genetic
  • Receptors, Cell Surface/genetics
  • Saccharomyces cerevisiae/immunology
  • Toll-Like Receptor 4
  • Toll-Like Receptors

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