@article{be32f7d6b3e546b6a68d455a3b8fac6d,
title = "The ultra-thin strut sirolimus-eluting coronary stent: SUPRAFLEX",
abstract = "Percutaneous coronary interventions with drug-eluting stents is currently the preferred revascularization treatment strategy for coronary artery disease. Following the first generation, the second-generation drug-eluting stents was designed with a thinner strut, better biocompatible polymer with/without bioresorbable coating or even polymer-free struts. The SUPRAFLEX stent system has ultra-thin struts (60 μm) across all stent diameters and a biodegradable polymer coating, enabling 70% of the sirolimus elution within 7 days. SUPRAFLEX has been assessed in large scale randomized controlled trials. This review summarizes the design of the SUPRAFLEX stent, the results of the pivotal clinical trials and outlines the ongoing research programs.",
keywords = "drug-eluting stents, percutaneous coronary intervention, ultra-thin struts",
author = "Chao Gao and Norihiro Kogame and Rodrigo Modolo and Kuniaki Takahashi and Rutao Wang and Hideyuki Kawashima and Masafumi Ono and Hironori Hara and Mariusz Tomaniak and Azfar Zaman and {de Winter}, {Robbert J.} and {van Geuns}, Robert-Jan and Upendra Kaul and Serruys, {Patrick W.} and Yoshinobu Onuma",
note = "Funding Information: R Modolo received research grant from Biosensors and SMT. RJ van Geuns received speakers{\textquoteright} fee from Abbott Vascular and Boston Scientific. PW Serruys reports personal fees from Biosensors, Sinomedical Sciences Technology, Philips/Volcano, Xeltis and Heart-Flow. A Zaman reports speakers{\textquoteright} fees from SMT and speaker and consulting fees from Abbott Vascular. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript. Publisher Copyright: {\textcopyright} 2021 Future Medicine Ltd.. All rights reserved.",
year = "2021",
month = mar,
day = "1",
doi = "https://doi.org/10.2217/fca-2019-0083",
language = "English",
volume = "17",
pages = "227--238",
journal = "Future cardiology",
issn = "1479-6678",
publisher = "Future Medicine Ltd.",
number = "2",
}