Abstract
This paper presents the three-dimensional strains in the normal human left ventricle (LV) at end-systole and during diastole. Magnetic resonance tissue tagging was used to measure strain in the left-ventricular heart wall in 10 healthy volunteers aged between 28 and 61 years. The three-dimensional motion was calculated from the displacement of marker points in short- and long-axis cine images, with a time resolution of 30 msec. Homogeneous strain analysis of small tetrahedrons was used to calculate deformation in 18 regions of the LV over a time span of 300msec starting at end systole. End-systolic radial strain was largest near the heart base, and circumferential and longitudinal strains were largest near the apex. During diastole, the circumferential-longitudinal shear strain (associated with LV torsion) was found to recover earlier than the axial strains. Assessment of three-dimensional diastolic strain is possible with MR tagging. Comparison of patient strain against normal strain may permit early detection of regional diastolic dysfunction.
Original language | English |
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Pages (from-to) | 341-351 |
Number of pages | 11 |
Journal | Journal of cardiovascular magnetic resonance |
Volume | 4 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2002 |
Keywords
- Diastole
- Left ventricle
- Left-ventricular function
- Magnetic resonance tagging
- Strain analysis