Tight regulation of the Epstein-Barr virus setpoint: interindividual differences in Epstein-Barr virus DNA load are conserved after HIV infection

Erwan Piriou; Karel van Dort; Sigrid Otto; Marinus H. J. van Oers; Debbie van Baarle

doi:https://doi.org/10.1086/524079

Tight regulation of the Epstein-Barr virus setpoint: interindividual differences in Epstein-Barr virus DNA load are conserved after HIV infection

Erwan Piriou, Karel van Dort, Sigrid Otto, Marinus H. J. van Oers, Debbie van Baarle

Research output: Contribution to journal › Article › Academic › peer-review

14 Citations (Scopus)

Abstract

Healthy individuals carry a constant number of Epstein-Barr virus-infected B cells in the peripheral blood over time. Here, we show that interindividual differences in Epstein-Barr virus DNA levels are maintained after HIV infection, providing evidence for the existence of an individual Epstein-Barr virus setpoint. Immune activation may contribute to the increase in this setpoint after human immunodeficiency virus seroconversion

Original language	English
Pages (from-to)	313-316
Journal	Clinical Infectious Diseases
Volume	46
Issue number	2
DOIs	https://doi.org/10.1086/524079
Publication status	Published - 2008

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https://doi.org/10.1086/524079

Cite this

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abstract = "Healthy individuals carry a constant number of Epstein-Barr virus-infected B cells in the peripheral blood over time. Here, we show that interindividual differences in Epstein-Barr virus DNA levels are maintained after HIV infection, providing evidence for the existence of an individual Epstein-Barr virus setpoint. Immune activation may contribute to the increase in this setpoint after human immunodeficiency virus seroconversion",

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