Transformation of an L-cell line with the DNA coding for the reduced-folate/methotrexate transporter protein from a CCRF-CEM human leukemia cell line

F E Williams, M Ratnam, T P McAlinden, G Jansen, J H Schornagel, J H Freisheim

Research output: Contribution to journalArticleAcademic

Original languageEnglish
Pages (from-to)779-82
Number of pages4
JournalAdvances in experimental medicine and biology
Publication statusPublished - 1993


  • Animals
  • Biological Transport
  • Carrier Proteins/biosynthesis
  • Cell Line
  • Cell Transformation, Neoplastic
  • Clone Cells
  • DNA, Neoplasm/metabolism
  • Folate Receptors, GPI-Anchored
  • Humans
  • Kinetics
  • L Cells (Cell Line)
  • Leukemia L1210/metabolism
  • Methotrexate/metabolism
  • Mice
  • Receptors, Cell Surface/biosynthesis
  • Transfection
  • Tumor Cells, Cultured

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