TY - GEN
T1 - Transformer-Based Deep Survival Analysis
AU - Hu, Shi
AU - Fridgeirsson, Egill A.
AU - van Wingen, Guido
AU - Welling, Max
PY - 2021
Y1 - 2021
N2 - In this work, we propose a new Transformer-based survival model which estimates the patient-specific survival distribution. Our contributions are twofold. First, to the best of our knowledge, existing deep survival models use either fully connected or recurrent networks, and we are the first to apply the Transformer in survival analysis. In addition, we use ordinal regression to optimize the survival probabilities over time, and penalize randomized discordant pairs. Second, many survival models are evaluated using only the ranking metrics such as the concordance index. We propose to also use the absolute error metric that evaluates the precise duration predictions on observed subjects. We demonstrate our model on two publicly available real-world datasets, and show that our mean absolute error results are significantly better than the current models, meanwhile, it is challenging to determine the best model under the concordance index.
AB - In this work, we propose a new Transformer-based survival model which estimates the patient-specific survival distribution. Our contributions are twofold. First, to the best of our knowledge, existing deep survival models use either fully connected or recurrent networks, and we are the first to apply the Transformer in survival analysis. In addition, we use ordinal regression to optimize the survival probabilities over time, and penalize randomized discordant pairs. Second, many survival models are evaluated using only the ranking metrics such as the concordance index. We propose to also use the absolute error metric that evaluates the precise duration predictions on observed subjects. We demonstrate our model on two publicly available real-world datasets, and show that our mean absolute error results are significantly better than the current models, meanwhile, it is challenging to determine the best model under the concordance index.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85171138274&origin=inward
M3 - Conference contribution
VL - 146
T3 - Proceedings of Machine Learning Research
SP - 132
EP - 148
BT - Proceedings of AAAI Spring Symposium on Survival Prediction - Algorithms, Challenges and Applications 2021
A2 - Greiner, Russell
A2 - Kumar, Neeraj
A2 - Gerds, Thomas Alexander
A2 - van der Schaar, Mihaela
PB - ML Research Press
T2 - 2021 AAAI Spring Symposium on Survival Prediction - Algorithms, Challenges and Applications, SPACA 2021
Y2 - 22 March 2021 through 24 March 2021
ER -