The administration of gonadotropin releasing hormone (GnRH) given in a very particular episodic way has established itself as the prime therapy for induction of ovulation in hypogonadotropic amenorrhea of supra-pituitary origin (WHO 1). The goal of pulsatile GnRH in ovulation induction is to obtain endogenous pituitary gonadotropin secretion that results in a preferably mono-ovulatory response of the ovaries. So a logical question is why not administer the gonadotropins straight away? In view of current highly advocated evidence-based medical practice lies this relatively straightforward question wide open because the literature provides absolutely insufficient data.
Original language | English |
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Title of host publication | Ovulation Induction: Evidence Based Guidelines for Daily Practice |
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Publisher | CRC Press |
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Pages | 81-86 |
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ISBN (Electronic) | 9781498704083 |
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ISBN (Print) | 9781498704076 |
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Publication status | Published - 26 Oct 2016 |
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Name | Ovulation Induction: Evidence Based Guidelines for Daily Practice |
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