Treatment Options for Weight Regain or Insufficient Weight Loss After Sleeve Gastrectomy: a Systematic Review and Meta-analysis

Rutger J. Franken, Nina R. Sluiter, Josephine Franken, Ralph de Vries, Dennis Souverein, Vitor E. A. Gerdes, Maurits de Brauw

Research output: Contribution to journalReview articleAcademicpeer-review

21 Citations (Scopus)

Abstract

Weight failure after sleeve gastrectomy (SG) is frequently observed. Consensus on the most effective treatment is lacking. The aim of this meta-analysis was to assess revisional strategies for weight regain (WR) or insufficient weight loss (IWL) following SG. The included studies reported on endoscopic gastroplasty (ESG), re-sleeve gastrectomy (re-SG), Roux-en-Y gastric bypass (RYGB), one-anastomosis gastric bypass (OAGB), single-anastomosis duodeno-ileal bypass (SADI), and duodenal switch (DS). All techniques resulted in clinically relevant weight loss. Although our data suggest that revisional OAGB was the most effective procedure, the lack of direct comparisons precludes strong conclusions. All procedures were feasible but differed regarding complication rates. Choice of procedure is depending on patient’s characteristics and surgeons’ expertise. Graphical abstract: [Figure not available: see fulltext.]
Original languageEnglish
Pages (from-to)2035-2046
Number of pages12
JournalObesity Surgery
Volume32
Issue number6
Early online date2022
DOIs
Publication statusPublished - Jun 2022

Keywords

  • Duodenal switch
  • Gastric bypass
  • Gastroplasty
  • Insufficient weight loss
  • Meta-analysis
  • One-anastomosis gastric bypass
  • Re-sleeve gastrectomy
  • Single-duodeno-ileal bypass
  • Sleeve gastrectomy
  • Weight regain

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