Treg subsets in inflammatory bowel disease and colorectal carcinoma: Characteristics, role, and therapeutic targets

Egbert H. van Herk; Anje A. te Velde

doi:https://doi.org/10.1111/jgh.13342

Treg subsets in inflammatory bowel disease and colorectal carcinoma: Characteristics, role, and therapeutic targets

Egbert H. van Herk, Anje A. te Velde

Research output: Contribution to journal › Review article › Academic › peer-review

25 Citations (Scopus)

Abstract

T regulatory cells (Tregs) play an important role in the regulation of autoimmunity, autoinflammation, allergic diseases, infection, and the tumor environment. Different subsets are characterized that use a number of regulatory mechanisms. Tregs can influence the progression of inflammatory bowel disease and the development of colorectal cancer. Knowledge of Tregs and their regulatory mechanisms can provide new targets for therapeutic intervention

Original language	English
Pages (from-to)	1393-1404
Journal	Journal of gastroenterology and hepatology
Volume	31
Issue number	8
DOIs	https://doi.org/10.1111/jgh.13342
Publication status	Published - 2016

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https://doi.org/10.1111/jgh.13342

Cite this

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title = "Treg subsets in inflammatory bowel disease and colorectal carcinoma: Characteristics, role, and therapeutic targets",

abstract = "T regulatory cells (Tregs) play an important role in the regulation of autoimmunity, autoinflammation, allergic diseases, infection, and the tumor environment. Different subsets are characterized that use a number of regulatory mechanisms. Tregs can influence the progression of inflammatory bowel disease and the development of colorectal cancer. Knowledge of Tregs and their regulatory mechanisms can provide new targets for therapeutic intervention",

author = "{van Herk}, {Egbert H.} and {te Velde}, {Anje A.}",

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AU - te Velde, Anje A.

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AB - T regulatory cells (Tregs) play an important role in the regulation of autoimmunity, autoinflammation, allergic diseases, infection, and the tumor environment. Different subsets are characterized that use a number of regulatory mechanisms. Tregs can influence the progression of inflammatory bowel disease and the development of colorectal cancer. Knowledge of Tregs and their regulatory mechanisms can provide new targets for therapeutic intervention

U2 - https://doi.org/10.1111/jgh.13342

DO - https://doi.org/10.1111/jgh.13342

M3 - Review article

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JO - Journal of gastroenterology and hepatology

JF - Journal of gastroenterology and hepatology

IS - 8

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