Tropical pyomyositis: an update

Adebayo Shittu, Stefanie Deinhardt-Emmer, Jonathan Vas Nunes, Silke Niemann, Martin P. Grobusch, Frieder Schaumburg

Research output: Contribution to JournalReview articleAcademicpeer-review

8 Citations (Scopus)

Abstract

Tropical pyomyositis (TP) is a life-threatening bacterial infection of the skeletal muscle that occurs particularly among children, young adults and those with immunocompromised conditions. The appropriate diagnosis and treatment are often delayed due to its non-specific signs, leading to fatal consequences. Staphylococcus aureus, especially methicillin-susceptible S. aureus, is responsible for most TP cases. However, other bacteria (i.e. streptococci, Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp., Candida spp., Mycobacterium spp.) have been reported. This narrative review provides an update on the epidemiology and clinical course of TP. A special focus is laid on the role of toxins (i.e. Panton-Valentine Leucocidin and α-toxin) in the pathogenesis of TP and their implication for the clinical management of infection.
Original languageEnglish
Pages (from-to)660-665
Number of pages6
JournalTropical Medicine & International Health
Volume25
Issue number6
Early online date2020
DOIs
Publication statusPublished - 1 Jun 2020

Keywords

  • Staphylococcus aureus
  • clinical course
  • epidemiology
  • pathogenesis
  • review
  • tropical pyomyositis

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