Ultrafiltration Failure

Watske Smit, Raymond T. Krediet

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Abstract

Ultrafiltration failure is one of the most important complications of peritoneal dialysis (PD). It is seen more frequently in patients treated with PD for a longer period of time, especially when residual urine production is absent. Ultrafiltration failure often leads to overhydration, which is probably the most important cause of cardiovascular death in PD patients. This chapter describes the mechanism of fluid transport during peritoneal dialysis and discusses the proper definition of ultrafiltration failure. It summarizes a variety of causes of homeostasis failure and practical guidelines are presented to make an appropriate diagnosis. The possible therapeutical measures are discussed extensively. Special interest is given to prevention of fluid overload in PD patients and in addition prospects for the future are debated.
Original languageEnglish
Title of host publicationNolph and Gokal’s Textbook of Peritoneal Dialysis
Subtitle of host publicationFourth Edition
PublisherSpringer International Publishing
Pages759-779
Number of pages21
ISBN (Electronic)9783030620875
ISBN (Print)9783030620868
DOIs
Publication statusPublished - 1 Jan 2023

Publication series

NameNolph and Gokal’s Textbook of Peritoneal Dialysis: Fourth Edition

Keywords

  • Advanced glycosylation products
  • Fluid transport
  • Free water transport
  • Hydrostatic pressure gradient
  • Overhydration
  • Peritoneal dialysis
  • Small pore fluid transport
  • Ultrafiltration failure
  • Vasculopathy

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