TY - JOUR
T1 - Ultrastructural pathology of the nuclear envelope in familial lamin A/C cardiomyopathy
AU - Diercks, Gilles F.
AU - van Tintelen, J. Peter
AU - Tio, Rene A.
AU - Kerstjens-Frederikse, Wilhelmina S.
AU - Pinto, Yigal M.
AU - Suurmeijer, Albert J.
PY - 2010
Y1 - 2010
N2 - The LMNA gene encodes lamins A and C, two structural proteins of the nuclear lamina, a part of the nuclear envelope. LMNA gene mutations may cause familial cardiomyopathy. In this article, we describe an electron microscopic image of an endomyocardial biopsy specimen of a subject with familial cardiomyopathy with early onset cardiac fibrosis due to a deletion in LMNA, showing structural damage of the nuclear envelope
AB - The LMNA gene encodes lamins A and C, two structural proteins of the nuclear lamina, a part of the nuclear envelope. LMNA gene mutations may cause familial cardiomyopathy. In this article, we describe an electron microscopic image of an endomyocardial biopsy specimen of a subject with familial cardiomyopathy with early onset cardiac fibrosis due to a deletion in LMNA, showing structural damage of the nuclear envelope
U2 - https://doi.org/10.1016/j.carpath.2009.03.001
DO - https://doi.org/10.1016/j.carpath.2009.03.001
M3 - Article
C2 - 19375354
SN - 1054-8807
VL - 19
SP - e135-e136
JO - Cardiovascular pathology
JF - Cardiovascular pathology
IS - 4
ER -