TY - JOUR
T1 - Validation of Two Screening Tools for Anxiety in Hemodialysis Patients
AU - Nadort, Els
AU - van Geenen, Noëlle J. K.
AU - Schouten, Robbert W.
AU - Boeschoten, Rosa E.
AU - Shaw, Prataap Chandie
AU - Vleming, Louis Jean
AU - Schouten, Marcel
AU - Farhat, Karima
AU - Dekker, Friedo W.
AU - van Oppen, Patricia
AU - Siegert, Carl E. H.
AU - Broekman, Birit F. P.
N1 - Funding Information: Funding: This work was supported by ZonMW (grant number: 843001804), the Dutch Kidney Foundation (project code: 20OP+021), Stichting Zabawas (donation number: 2020/605), and Stichting Wetenschappelijk Onderzoek OLVG. The funders did not have any role in the study design, the writing of the report, or the decision to submit the report for publication. The OLVG Hospital has full ownership of the data collected in this study. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/7/1
Y1 - 2022/7/1
N2 - Background: Symptoms of anxiety are often unrecognized and untreated in dialysis patients. We investigated the diagnostic accuracy of two widely used screening tools for anxiety in hemodialysis patients. Methods: For this cross-sectional validation study, chronic hemodialysis patients from eight dialysis centers in the Netherlands were included. The Beck Anxiety Inventory (BAI) and Hospital Anxiety and Depression Scale—Anxiety subscale (HADS-A) were validated by the Mini International Neuropsychiatric Inventory (MINI) diagnostic interview. Receiver operating characteristic curves were used to determine the optimal cut-off values. Results: Of 65 participants, 13 (20%) were diagnosed with one or more anxiety disorders on the MINI, of which 5 were included in the analysis. ROC curves showed a good diagnostic accuracy of the BAI and HADS-A. The optimal cut-off value for the BAI was ≥13 (sensitivity 100%, specificity 85%) and for the HADS-A was ≥10 (sensitivity 80%, specificity 100%). Conclusions: Based on our limited data, both the BAI and the HADS-A seem to be valid screening instruments for anxiety in hemodialysis patients that can be used in routine dialysis care. The HADS-A consists of fewer items and showed fewer false-positive results than the BAI, which might make it more useful in clinical practice.
AB - Background: Symptoms of anxiety are often unrecognized and untreated in dialysis patients. We investigated the diagnostic accuracy of two widely used screening tools for anxiety in hemodialysis patients. Methods: For this cross-sectional validation study, chronic hemodialysis patients from eight dialysis centers in the Netherlands were included. The Beck Anxiety Inventory (BAI) and Hospital Anxiety and Depression Scale—Anxiety subscale (HADS-A) were validated by the Mini International Neuropsychiatric Inventory (MINI) diagnostic interview. Receiver operating characteristic curves were used to determine the optimal cut-off values. Results: Of 65 participants, 13 (20%) were diagnosed with one or more anxiety disorders on the MINI, of which 5 were included in the analysis. ROC curves showed a good diagnostic accuracy of the BAI and HADS-A. The optimal cut-off value for the BAI was ≥13 (sensitivity 100%, specificity 85%) and for the HADS-A was ≥10 (sensitivity 80%, specificity 100%). Conclusions: Based on our limited data, both the BAI and the HADS-A seem to be valid screening instruments for anxiety in hemodialysis patients that can be used in routine dialysis care. The HADS-A consists of fewer items and showed fewer false-positive results than the BAI, which might make it more useful in clinical practice.
KW - anxiety disorders
KW - mass screening
KW - renal dialysis
UR - http://www.scopus.com/inward/record.url?scp=85133521293&partnerID=8YFLogxK
U2 - https://doi.org/10.3390/jpm12071077
DO - https://doi.org/10.3390/jpm12071077
M3 - Article
C2 - 35887577
SN - 2075-4426
VL - 12
JO - Journal of Personalized Medicine
JF - Journal of Personalized Medicine
IS - 7
M1 - 1077
ER -