Abstract
Background: Neurocognitive abnormalities are prevalent in both first episode schizophrenia patients and in ultra high risk (UHR) patients. Aim: To compare verbal fluence performance at baseline in UHR in patients that did and did not make the transiton to psychosis. Method: Baseline verbal fluence performanace in UHR-patients (n=47) was compared to match first episode patients (n=69) and normal controls (n=42) Results: Verbal fluency (semantic category) score in UHR-patients did not differ significantly from the score in first episode schizophrenia patients. Both the UHR group (p <0.003) and the patient group (p <0.0001) performed significantly worse than controls. Compared to the non-transition group, the transition group performed worse on verbel fluency, semantic category (p <0.006) at baseline. Conclusions: Verbel fluency (semantic category) is disturbed in UHR-patients that make the transition to psychosis and could contribute to an improved prediction of transition to psychosis in UHR-patients. (C) 2009 Elsevier Masson SAS. All rights reserved
Original language | English |
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Pages (from-to) | 105-110 |
Journal | European psychiatry |
Volume | 25 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2010 |